OLAW: Office of Laboratory Animal Welfare News Archive - 2004
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News Archive: 2004

News Archive Table Of Contents
Date News Flash Description
January 10, 2005 ILAR Journal Announcement January 2005
January 7, 2005 "Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research" (PDF) (Requires Acrobat Reader 6.0 or above) Copyright 2003 by the National Academy of Sciences. All rights reserved.
December 23, 2004 Training in Basic Biomethodology for Laboratory Mice
December 8, 2004 IACUC 101 and PRIMR/ARENA Annual IACUC Meeting, March, 2005
October 13, 2004 ILAR Announces, "Animal Models and Experimental Design Considerations for Endocrine Disruptor Research and Testing"
October 13, 2004 Texas Workshop on New Challenges in Research Programs and Technology
August 10, 2004 November 2 IACUC 101 Training to be held in State College, Pennsylvania
July 13, 2004 OER Notice Regarding Animal Welfare Documents Submitted to OLAW
June 22, 2004 ILAR Announces, "Advances in Diabetes Through Animal-Related Research"
June 22, 2004 Senior Level OLAW Positions Announced
June 21, 2004 September SCAW Advanced IACUC Workshop in Denver
June 10, 2004 September 14 IACUC 101 Training Session to be held in Irvine, California
May 14, 2004 July 13 and 14 IACUC 101 & 201 Workshops in Durham, North Carolina
May 12, 2004 5/14 Webcast of Free-Ranging Wildlife Meeting
April 23, 2004 ILAR Announces, "Nonhuman Primate Models and Other Animal Models of Women's Health"
March 11, 2004 June 28 IACUC 101 Training Session to be held in Detroit
February 27, 2004 April SCAW Advanced IACUC Workshop in New York
February 23, 2004 June 29-30 Workshop on Animal Welfare and Good Laboratory Practices in Detroit
January 30, 2004 SCAW Advanced IACUC Workshop in Baltimore, March 2004
January 29, 2004 Northwest Association for Biomedical Research IACUC Workshop in March
January 15, 2004 “IACUC 101 for Scientists” at EB 2004
January 14, 2004 ILAR Report, "National Needs and Priorities for Veterinarians in Biomedical Research”


News Flash Items
ILAR Journal Announcement January 2005

ILAR Journal January 2005

ILAR Journal Volume 46(1), "Infectious Disease Research in the Age of Biodefense" offers insight into regulatory, budgetary, safety, public relations, and resource issues associated with infectious disease research since the advent of the war on terrorism and the refocusing of US research efforts on biodefense.

Topics in this issue include new regulations and restrictions regarding select agents; approaches to infectious disease containment for laboratory and agricultural animal research; one institution’s experience in communicating with the public regarding infectious disease research; facility design recommendations; and administrative concerns due to shifts in research priorities. Article titles include the following:

  • Hidden Costs of Biodefense Research
  • Select Agent Regulations
  • Administrative Issues Related to Infectious Disease Research in the Age of Bioterrorism
  • Demand for Nonhuman Primate Resources in the Age of Biodefense
  • Facility Design Considerations for Select Agency Animal Research
  • Issues Related to the Use of Animals in Biocontainment Research Facilities
  • Working with Transmissible Spongiform Encephalopathy Agents
  • Veterinary Medicine in the 21st Century: The Challenge of Biosecurity
  • Public Response to Infectious Disease Research: The UC Davis Experience

To order this issue online, go to http://www.nationalacademies.org/pr4601, or call 202-334-2590, or e-mail: ILAR@nas.edu.

Publication of this issue of the ILAR Journal is supported by a grant from the NIH (5 P-40-RR-11611).

Training in Basic Biomethodology for Laboratory Mice

The National Human Genome Research Institute Office of Laboratory Animal Medicine has developed a training CD in Basic Methodology for Laboratory Mice. The CD illustrates the most common practices used in the NIH intramural research program and was developed to promote proficiency in performing common techniques in the mouse. It consists of eight training modules, table of contents, list of definitions and help and reference sections.

To obtain a copy of the CD send your name, research institution affiliation, full mailing address and email address to: rodent-cd@mail.nih.gov. Once CD per request please.


IACUC 101 and PRIMR/ARENA Annual IACUC Meeting, March, 2005

The Office of Laboratory Animal Welfare/NIH (OLAW) will join Public Responsibility in Medicine and Research (PRIM&R) and Applied Research Ethics National Association (ARENA) in co-sponsoring an IACUC 101 on March 13 and “Communication, Cooperation, Collaboration…The Cornerstones of an Effective Animal Care and Use Program” on March 14-15, 2005, in San Diego, California. Additional co-sponsorship commitments have been received from the Association for Assessment and Accreditation of Laboratory Animal Care International, Animal and Plant Health Inspection Service of the U.S. Department of Agriculture, and the University of California, San Diego. The IACUC 101 is a full day didactic and interactive course for new as well as seasoned IACUC members, IACUC affiliates and individuals responsible for their institution’s animal care program. Participants will receive an extensive Resources Manual plus other valuable reference materials and information. The PRIM&R and ARENA’s Annual IACUC Conference will focus on the effects of the veterinary shortage, use of animals in stem cell and biodefense research, semiannual inspections, and continuing concerns about the use of transgenics. The conference will be designed to be relevant and of interest to IACUC participants of all levels of experience.

Conference agendas will be posted and registration information for both meetings are available at: http://www.primr.org/education/2005_IACUC/overview_IA05.html.


ILAR Announces, "Animal Models and Experimental Design Considerations for Endocrine Disruptor Research and Testing"
ILAR Journal

Volume 45(4) of the ILAR Journal discusses the use of diverse animal models in endocrine disruptor research and testing, including invertebrates, birds, small fish, knockout mice, and rodents. This issue highlights the many environmental factors that can confound endocrine disruptor research such as single or group housing, cage type, ventilation, environmental enrichment, and particularly diet.

Articles in this issue include:

  • Selecting Appropriate Animal Models and Experimental Designs for Endocrine Disruptor Research and Testing Studies
  • Commentary: Setting Aside Tradition When Dealing with Endocrine Disruptors
  • Selecting the Appropriate Rodent Diet for Endocrine Disruptor Research and Testing Studies
  • Laboratory Animal Science Issues in the Design and Conduct of Studies with Endocrine-active Compounds
  • Use of the Laboratory Rat as a Model in Endocrine Disruptor Screening and Testing
  • Animal Models and Studies of in Utero Endocrine Disruptor Effects
  • Behavioral Effects of Endocrine-disrupting Substances: Phytoestrogens
  • Estrogen Receptor Knockout Mice as a Model for Endocrine Research
  • Factors Considered in Using Birds for Evaluating Endocrine-disrupting Chemicals
  • Small Fish Models for Identifying and Assessing the Effects of Endocrine-disrupting Chemicals.
  • Use and Role of Invertebrate Models in Endocrine Disruptor Research and Testing
  • In Vitro Models for Endocrine Disruptor Screening
  • using NSY and NOD mouse models.

This issue may be purchased for $25 online To order this issue online, go to www.national-academies.org/ilarjournal, or call 202-334-2590, or e-mail ILARJ@nas.edu.

Publication of this issue of the ILAR Journal is supported by a grant from the NIH (5 P-40-RR-11611).


Texas Workshop on New Challenges in Research Programs and Technology

The Office of Laboratory Animal Welfare, NIH, the Scientists Center for Animal Welfare (SCAW), and the University of Texas Health Sciences Center at San Antonio will present the SCAW Winter Conference, “21st Century Challenges: Keeping Pace with Changing Research Programs and Technology.” The meeting will be held December 6-7, 2004, at The Menger Hotel in San Antonio, Texas. The SCAW workshop will include topics such as Infectious disease research, biohazards and select agents, facility construction and renovation, and new animal enrichment practices. The conference agenda and a registration form are available at the SCAW website, http://scaw.com/conference.htm.


November 2 IACUC 101 Training to be held in State College, Pennsylvania
The Office of Laboratory Animal Welfare (OLAW), National Institutes of Health, will co-sponsor an IACUC 101 Workshop with the Pennsylvania State University on November 2. IACUC 101 is a full-day didactic and interactive training course. Participants will receive an extensive Resources Manual plus other valuable reference materials and information. The session will be held at the Nittany Lion Inn at the Pennsylvania State University, www.pshs.psu.edu/nittanylioninn/nlhome.asp, (800) 233-7505. For more information about the IACUC 101 Workshop, contact Melanie Freeman at (814) 865-1775; or Mary Lou James, mljames@mo.net.

The program and registration information are posted at www.research.psu.edu/orp/ANI/IACUC101/iacuc_home.htm.


OER Notice Regarding Animal Welfare Documents Submitted to OLAW

On July 13, 2004 a notice was published in the NIH Guide to Grants and Contracts announcing changes related to two required documents for institutions holding Animal Welfare Assurances with the NIH. Assurances will be approved for periods of up to four years and awardee institutions are strongly encouraged to use the calendar year for the reporting period of annual reports. The notice can be found at: http://grants.nih.gov/grants/guide/notice-files/NOT-OD-04-052.html.


ILAR Announces, "Advances in Diabetes Through Animal-Related Research"

ILAR Journal

Volume 45(3) of the ILAR Journal focuses largely on the subject of Type 1 diabetes, or insulin-dependent diabetes mellitus. The various articles within this issue were chosen to illustrate the international scope of diabetes research, the wide variety of animal models utilized in diabetes research, and the diverse areas of inquiry that are currently being pursued.

Articles in this issue explore:

  • The etiology of autoimmunity in the nonobese diabetic (NOD) mouse, a spontaneous model of Type 1 diabetes.
  • Animal models used to study adult stem cell-derived, in vitro-generated islet implantation.
  • A review of viral-induced Type 1 diabetes in rodent models.
  • A study of cross-species physiological incompatibilities in xenotransplantation utilizing the tilapia fish model.
  • Use of the Göttingen minipig as a model of Type 1 diabetes, similarities to human physiological and pathophysiological responses.
  • An examination of shared genetic susceptibility between Type 1 and Type 2 diabetes using NSY and NOD mouse models.

This issue may be purchased for $25 online To order this issue online, go to www.national-academies.org/ilarjournal, or call 202-334-2590, or e-mail ILARJ@nas.edu.

Publication of this issue of the ILAR Journal is supported by a grant from the NIH (5 P-40-RR-11611).


Senior Level OLAW Positions Announced

NIH is seeking applications from exceptional candidates for two senior level positions in the Office of Laboratory Animal Welfare. The positions, Director, Office of Laboratory Animal Welfare, and Director, Division of Compliance Oversight, OLAW, are announced at: http://grants.nih.gov/grants/oer_vacancies.htm. Questions regarding these solicitations should be addressed to oervacancies@od.nih.gov or by leaving a voice message at 301-435-2735.

Dr. Stephen Potkay retired May 1, 2004 and Dr. Axel Wolff is Acting Director, Division of Compliance Oversight. Dr. Nelson Garnett retired June 1, 2004 and Ms. Carol Wigglesworth is Acting Director, OLAW.


September SCAW Advanced IACUC Workshop in Denver

The NIH Office of Laboratory Animal Welfare will join the Scientists Center for Animal Welfare, the University of Colorado Health Sciences Center, and the National Jewish Medical & Research Center in co-sponsoring an advanced training course for members of Institutional Animal Care and Use Committees on September 17, 2004. It will be held at the DoubleTree Hotel, 3203 Quebec Street, Denver, Colorado. IACUC-Advanced is a new program to train members of Institutional Animal Care and Use Committees (IACUCs). This workshop is for experienced IACUC members and others who work with laboratory animals. The program will include small discussion groups and sharing of information among the participants on issues and controversies involving compliance with Federal laws and regulations in research activities involving animals.

The latest program is posted at http://www.scaw.com/iacuc-advanced%20program%20CO.htm and registration information is posted at http://www.scaw.com/iacuc%20advanced%20registration.pdf.


September 14 IACUC 101 Training Session to be held in Irvine, California

The Office of Laboratory Animal Welfare (OLAW), National Institutes of Health, will co-sponsor an IACUC 101 Workshop with the California Biomedical Research Association, and the University of California, Irvine, on September 14. IACUC 101 is a full day didactic and interactive training course. Participants will receive an extensive Resources Manual plus other valuable reference materials and information. The session will be held at Atrium Hotel, http://www.atriumhotel.com or (949) 833-2770. For more information about the IACUC 101 Workshop, contact Cindy Larsen, UCI clarsen@uci.edu; Desirée Glaspey, CBRA dglaspey@ca-biomed.org; or Mary Lou James mljames@socket.net.

The program and registration information are posted at Irvine_061004.doc



July 13 and 14 IACUC 101 & 201 Workshops in Durham, North Carolina

On Tuesday, July 13, and Wednesday, July 14, 2004, in Durham, North Carolina, the North Carolina Association for Biomedical Research, the NIH Office of Laboratory Animal Welfare, and the University of North Carolina at Chapel Hill will co-sponsor two days of IACUC training at the Sheraton Imperial Hotel and Convention Center. The first day is a traditional IACUC 101 course, which is a full day didactic and interactive training course that provides a basic yet comprehensive overview of the laws, regulations, and policies that govern the humane care and use of laboratory animals with examples and possible approaches for successful and effective administration. The second day is a special IACUC 201 course, which is a highly interactive program that takes the fundamentals of IACUC 101 and applies them to the process and mechanisms of ensuring compliance with a mock IACUC in the afternoon session to address complex scenarios.

The program and registration information are posted at http://www.ncabr.org/org/iacuc.asp.


5/14 Webcast of Free-Ranging Wildlife Meeting

The May 14, 2004 meeting on Research with Free-Ranging Wildlife: IACUC Review of Projects Regulated by Multiple Agencies, hosted by the University of Alaska Fairbanks and supported by OLAW and the National Science Foundation, will be offered via live webcast.

Please visit the following website for details about the May 14 meeting, including the agenda and biosketches of the speakers: http://www.uaf.edu/iacuc/iacuc_101/

The May 13 IACUC 101 will not be webcast, except to selected locations in Alaska. NOTE THAT TIMES ON THE AGENDA ARE ALASKA TIME! 8:30am in Alaska will be 12:30pm on the east coast and 9:30 am on the west coast. The webcast may be viewed from the following url: http://cat.uaf.edu/video

To view the streaming video you must have the login and password which can be obtained by sending an e-mail containing the following information to: fyiacuc@uaf.edu
Name:
Affiliation:
Address:
e-mail:
phone number:
estimated number of people viewing from your site:


ILAR Announces, "Nonhuman Primate Models and Other Animal Models of Women's Health"
ILAR Journal Cover

The Institute for Laboratory Animal Research (ILAR) is announcing publication of the newest issue of the ILAR Journal titled "Nonhuman Primate Models and Other Animal Models of Women’s Health,” Vol. 45, No. 2. This issue cites the advances in women’s health research through the use of animals. Articles discuss the role of hormones in pre- and post-menopausal diseases, such as polycystic ovarian syndrome, endometriosis, coronary heart disease, stroke, insulin resistance and diabetes, osteoporosis, reproductive tract cancers, cognitive decline, and mood disorders. This issue also discusses the role of stress, exercise, and caloric restriction on ovarian dysfunction, and the positive and negative effects of soy on women’s health.

To view the table of contents or to order this issue online go to http://dels.nas.edu/ilar/journal_home.asp, or call (202) 334-2590, or e-mail ILARJ@nas.edu.

Publication of this issue of the ILAR Journal is supported by a grant from the NIH (5 P-40-RR-11611).


June 28 IACUC 101 Training Session to be held in Detroit

The Office of Laboratory Animal Welfare (OLAW), National Institutes of Health, will co-sponsor an IACUC 101 Workshop with the Michigan Society for Medical Research in Detroit, Michigan, on June 28. IACUC 101 is a full day didactic and interactive training course. Participants will receive an extensive Resources Manual plus other valuable reference materials and information. The session will be held at The Westin Detroit Metropolitan Airport http://www.starwood.com/westin/index.html or 1-800-937-8461. For more information about the IACUC 101 Workshop, contact mismr@umich.edu.

Announcement and registration information are posted at: http://grants.nih.gov/grants/olaw/westin_062804.doc


April SCAW Advanced IACUC Workshop in New York

The NIH Office of Laboratory Animal Welfare will join the Scientists Center for Animal Welfare, Rockefeller University, and Weill Medical College of Cornell University in co-sponsoring an advanced training course for members of Institutional Animal Care and Use Committees on April 15, 2004. It will be held at Weiss Hall at Rockefeller University in New York. IACUC-Advanced is a new program to train members of Institutional Animal Care and Use Committees (IACUCs). This workshop is for experienced IACUC members and others who work with laboratory animals. The program will include small discussion groups and sharing of information among the participants on issues and controversies involving compliance with Federal laws and regulations in research activities involving animals.

The latest program is posted at http://grants.nih.gov/grants/olaw/scawadviacucny.doc and registration information is posted at http://www.scaw.com/iacuc-advanced.htm.


June 29-30 Workshop on Animal Welfare and Good Laboratory Practices in Detroit

The Office of Laboratory Animal Welfare (OLAW) will co-sponsor a focused workshop, Balancing Animal Welfare and Regulatory Compliance Issues in Preclinical Studies, with the Department of Pharmacology and Toxicology, Michigan State University, on June 29-30, 2004, in Detroit, Michigan. Additional co-sponsors include the Food and Drug Administration, Michigan Society for Medical Research, and the Animal and Plant Health Inspection Service, USDA. The conference will bring together internationally recognized leaders of the scientific and regulatory communities to identify the issues and to discuss harmonization of animal welfare standards in biomedical research. Additional information is posted at http://grants.nih.gov/grants/olaw/westin_062904.doc


SCAW Advanced IACUC Workshop in Baltimore, March 2004

The NIH Office of Laboratory Animal Welfare will join the Scientists Center for Animal Welfare and the Johns Hopkins University (JHU) in co-sponsoring an advanced training course for members of Institutional Animal Care and Use Committees on March 5, 2004. It will be held at the Turner Building, JHU East Campus. The meeting will focus on complex topics arising about the welfare of animals in research. The program will include small discussion groups and sharing of information among the participants concerning issues and controversies involving compliance with Federal laws and regulations in research activities involving animals. The program and registration information are posted at http://www.scaw.com/iacuc-advanced.htm.


Northwest Association for Biomedical Research IACUC Workshop in March

The NIH Office of Laboratory Animal Welfare (OLAW) will join the Northwest Association for Biomedical Research (NWABR), AMGEN, SNBL, and ICOS in co-sponsoring a Regional Education Conference. The IACUC Workshop, “Building an Effective IACUC: The Basics and Beyond,” will be held on March 8, 2004, in Bellevue, Washington. The agenda will focus on topics of interest to IACUCs and will be designed to provide information and opportunities for discussion regarding the role of IACUCs, their functions and responsibilities and ways to effectively discharge their responsibilities under the PHS Policy and related Guide for the Care and Use of Laboratory Animals. There will be sessions designed for novices and some for more experienced participants. Case studies addressing complex situations requiring professional judgment will also be included.

The program and registration information are posted on the NWABR website, http://www.nwabr.org/, or you can contact awatkins@nwabr.org for additional information.


“IACUC 101 for Scientists” at EB 2004

A half-day workshop on the Institutional Animal Care and Use Committees (IACUCs) will be offered at Experimental Biology 2004. “IACUC 101 for Scientists: Dealing with Problem Areas” will be presented from 11 am -3 pm on Saturday, April 17, 2004 in Room 146B of the Washington Convention Center. There is no separate fee for this session, but you register for EB 2004 to participate, and seating is limited so you are also encouraged to contact the APS Public Affairs Office to reserve a spot.

“IACUC 101 for Scientists” has been adapted from the popular “IACUC 101” training series created by the Applied Research Ethics National Association (ARENA). This workshop will provide information useful both to IACUC members and to researchers whose protocols require IACUC review. The EB 2004 workshop will move beyond IACUC basics to address areas that require special attention from IACUCs. Topics will include the role of the IACUC as a facilitator of research; the semi-annual review; designated member vs. full committee reviews; comparing grants to protocols; post-approval monitoring of protocols; institutional responsibilities; and creating a culture of compliance. Time is allotted within the program for participants to raise questions with representatives of USDA, OLAW, and AAALAC.

Participation of women, racial/ethnic minorities and persons with disabilities, and others who have been traditionally underrepresented in science is encouraged. If you have questions or need additional assistance, please contact Alice Ra’anan at (301) 634-7105 or araanan@the-aps.org

You must be registered for the Experimental Biology meeting to participate, but there is no separate fee for this session. The program and registration information are posted at http://www.the-aps.org/pa/IACUC/eb04.htm.


ILAR Report, "National Needs and Priorities for Veterinarians in Biomedical Research”
Book Cover of "National Needs and Priorities for Veterinarians in Biomedical Research"

The Institute for Laboratory Animal Research (ILAR) has announced publication of its newest report titled "National Needs and Priorities for Veterinarians in Biomedical Research."

This report identifies various factors which contributed to creating an unfulfilled need for veterinarians in the biomedical research workforce, including an increase in the number of NIH grants utilizing animals and the burgeoning use of transgenic rodents, without a comparable change in the supply of appropriately-trained veterinarians. The committee developed strategies for recruiting more veterinarians into careers in biomedical research.

This report may be viewed and purchased in PDF or purchased in paperback from the National Academy Press at http://www.nap.edu/catalog/10878.html.

Publication of this issue of the ILAR Journal is supported by a grant from the NIH (5 P-40-RR-11611).


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