Full Text LM-96-002 MEDICAL INFORMATICS RESEARCH TRAINING PROGRAMS NIH GUIDE, Volume 25, Number 12, April 19, 1996 RFA: LM-96-002 P.T. 44 Keywords: 0710078 National Library of Medicine Letter of Intent Receipt Date: June 3, 1996 Application Receipt Date: June 19, 1996 PURPOSE The National Library of Medicine invites grant applications in a single competition for support of predoctoral and postdoctoral training programs in medical informatics research. Applications may be for the creation of new training centers or for the renewal of existing NLM-supported training programs. Applications may be for the creation of new training centers or for the renewal of existing NLM-supported training programs. Such training will help meet a growing need for qualified, talented investigators, well prepared to address information problems in health care, health profession's education, biomedical research, health services research, and public health. These investigators will contribute to the growth of science by their studies of knowledge management and by advancing the frontiers of the computer sciences for acquiring, organizing, retrieving, and utilizing health knowledge. The expectation is that trainees will become able, cross-disciplinary informatics specialists. HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2000," a PHS-led national activity for setting priority areas. This Request for Applications (RFA), Medical Informatics Research Training, is related to the priority area of surveillance and data systems. Potential applicants may obtain a copy of "Healthy People 2000" (Full Report: Stock No. 017-001-00474-0 or Summary Report: Stock No. 017-001-00473-1) through the Superintendent of Documents, Government Printing Office, Washington, DC 20402-9325 (telephone 202-512-1800). ELIGIBILITY REQUIREMENTS Domestic, public and private, non-profit institutions engaged in health sciences' administration, education, research, and/or clinical care are eligible to apply. "Health sciences" is defined as medicine, dentistry, nursing, public health, pharmacy, veterinary medicine, and other sciences related to health. Racial/ethnic minority individuals, women, and those with disabilities are encouraged to apply. Groups (or cooperatives) of health-related institutions are also eligible to apply. A single, lead institution must apply on behalf of the group; letters of agreement defining mutual responsibilities must be provided in the application and signed by authorized officials of each participating institution. MECHANISM OF SUPPORT This RFA will use the continuing education training grant (T15) mechanism. These awards are authorized by the Medical Library Assistance Act and are not a part of the National Research Service Awards Program of the Public Health Service. However, the policies and requirements of the NLM program are similar to Public Health Service National Research Service Awards. Trainees must be citizens or non-citizen nationals of the United States or have been lawfully admitted for permanent residence at the time of appointment. Individuals on temporary or student visas are not eligible. Predoctoral students who have been accepted as candidates for the doctor of philosophy of science or equivalent degree at their institutions may be appointed as predoctoral trainees for a period not to exceed three years. Individuals who wish to interrupt their medical, veterinary, dental, or other professional school studies for a year or more to engage in full-time research training before completing their professional degrees are eligible. The current stipend level for predoctoral individuals at all levels of experience is $10,008 per annum. Postdoctoral individuals must have received, as of the beginning date of appointment, a Ph.D., M.D., D.O., D.D.S., D.V.M., O.D., D.P.M., Sc.D., Eng.D., Dr.P.H., D.N.Sc., or equivalent degree from an accredited domestic or foreign institution. Certification by an authorized official of the degree-granting institution that all degree requirements have been met is acceptable. The postdoctoral stipend for the first year of support is determined by the number of years of relevant postdoctoral experience at the time of appointment. Relevant experience may include research experience (including industrial), teaching, internship, residency, or other time spent in full-time studies in a health-related field beyond that of the qualifying doctoral degree. The stipend for each additional year of support is the next level on the stipend structure. Current postdoctoral stipends are as follows: Years of Relevant Experience Stipend 0 $19,608 1 $20,700 2 $25,600 3 $26,900 4 $28,200 5 $29,500 6 $30,800 7 or more $32,300 Stipends may be supplemented by an institution from non-Federal funds. No Federal funds may be used for stipend supplementation unless specifically authorized under the terms of the program from which funds are derived. Under no circumstances may the conditions of stipend supplementation detract from or prolong the training. Tuition, fees, and self-only health insurance are allowable trainee costs if such charges are required of all persons in a similar training status at the institution, without regard to their source of support. These costs will be fully reimbursed up to $2,000 plus 60 percent of such costs above $2,000. Tuition at the postdoctoral level is limited to that required for specific courses in support of the approved training program. Costs of trainee travel, including attendance at scientific meetings which the institution determines to be necessary to the individual's training, may be requested. Institutional costs of up to $1,500 per year per predoctoral trainee and up to $2,500 per year per postdoctoral trainee may be requested to defray the costs of training-related expenses such as staff salaries, consultant costs, equipment, research supplies, staff travel, and other expenses. The availability of funds may modify the maximum levels of institutional costs awarded. An indirect cost allowance based on eight percent of total allowable direct costs or actual, whichever is less, may be requested. In their proposed budgets, applicants should request trainee travel funds for a two-day meeting each year, to be held at the National Library of Medicine in Bethesda or at one of the training sites. The purpose of these meetings will be to exchange information among trainees, program directors, NLM program staff, and other selected participants. Short-term traineeships are available for students in medical or other professional schools of the health sciences. Such training is intended to give a limited number of selected students summer or "off-quarter" opportunities for involvement in research so that they might consider medical informatics as a career option. Students selected should be encouraged to have two or more short-term training appointments during the period of their professional school years, thus giving an individual student multiple periods of exposure to research training. Senior students would not normally be eligible for a first appointment to a short-term traineeship; exceptions may be requested from NLM. The stipend level for such short-term traineeships is prorated at a $10,008 annual rate. Recognizing that training programs of this nature require reasonably long-term continuity, NLM is prepared to approve awards for five-year periods. At an appropriate time, the availability of renewal support for these training program grants will be announced. FUNDS AVAILABLE NLM plans to make available approximately $4,000,000 for this program in FY 1997. It is expected that about ten training grants will be awarded; however, an actual award of grants pursuant to this RFA is necessarily contingent upon receipt of funds appropriated for this purpose. The specific number will also depend upon the merit and scope of applications received. RESEARCH OBJECTIVES Background Medical informatics goes beyond the use of the computer as a computational tool and extends into the process of knowledge representation, acquisition, storage, retrieval, and manipulation largely to support reasoning and decision-making. Although postdoctoral candidates for training should be clearly destined for health research careers in this field, their doctorates may have been earned in any appropriate field of endeavor, such as medicine, dentistry, nursing, computer science, engineering or any of the biological sciences. Sites should be academic medical centers; however, consortium training arrangements with other graduate schools and institutions are encouraged. Objectives and scope Acceptable applications must clearly indicate that the primary intent of the program preparation is for a career in medical informatics research. Applications must describe the process by which trainees will become familiar with the many relevant disciplines. To prepare trainees for careers in a demanding research environment, the sponsorship of a research-oriented, academic health sciences institution is critical. It is expected that the core of training will emphasize the synthesis, organization, retrieval, and effective management of knowledge. The curricula should be interdisciplinary - - involving medicine and other health related professions, the biological sciences, the cognitive sciences, information science, and computer science. Training sites must offer an excellent setting for instruction, involvement in important health-related computer research, and opportunities for meaningful trainee involvement in such research. In addition to the general goal of assisting in the education of persons who can take academic positions to conduct research and teach medical informatics, several more specialized additions will be available to enhance the research training programs. Some potential enhancement areas (described in the following paragraphs) are high performance computing and communication, biotechnology, health services research and public health, cancer, dental, and nursing information systems. Additional training slots may become available to those who provide training in these special areas. Applicants are encouraged to indicate their experience in any of these enhancement areas, and to indicate those areas (if any) in which they may plan to offer training experience, or in which they could in the future accept candidates for training. High performance computers and high speed computer networks are key technologies for modern science. These activities include creation and transmission of digital electronic images, linking of academic health centers via the future high performance communication networks, and development of advanced methods of retrieving biomedical information (as well as molecular biology computing, and training in informatics). The establishment within NLM of the National Center for Biotechnology Information intensifies the Library's interest and responsibilities in this special area of informatics. The appearance of new experimental methods has greatly increased the rate at which data are accumulating about the molecular control of life processes. Because of their enormous size and complexity, the vast data accumulations can only be analyzed and compared by sophisticated computer methodologies. Applicants are urged to include training in biotechnology informatics in their proposed curriculum, if such training is feasible and appropriate for the institution. The establishment within NLM of the National Information Center for Health Services Research and Health Care Technology (NICHSR) underscores NLM's commitment to improving information support for health services research. The development of computer-based patient record systems should allow automatic generation of some health services research data and public health data as a by-product of individual patient care. There are many complex and important informatics issues related to the anonymization, transmission, aggregation, and analysis of large amounts of patient data for health services research and public health surveillance. Applicants are urged to include training in health services research and public health informatics, if such training is feasible and appropriate for the institution. The National Cancer Institute (NCI) plans to make available up to $120,000 through this RFA. These funds would support trainees whose projects deal with the application of medical informatics approaches to the problems of cancer diagnosis and therapy. For support under this special training track, applicants should request consideration for funding by NCI and should describe how their projects will be of benefit to the field of cancer. The sponsoring institution must indicate its awareness of and commitment to the application of medical informatics to oncologic research that is relevant to the diagnosis and treatment of cancer. The purpose of this special training track is to stimulate qualified candidates to apply for postdoctoral Medical informatics training in areas that deal directly with cancer-related topics. When possible, the curricula should be interdisciplinary --involving an oncology discipline, cognitive sciences, information sciences and/or computer science. The National Institute of Dental Research (NIDR) plans to support through this RFA up to three trainees at a total cost of no more than $90,000. The training positions will be distributed among one or more sites depending on the relevance and assessment of proposed programs. The objective of this effort is to develop highly qualified investigators committed to a research career in oral health informatics, which integrates and applies the computer, information, and cognitive sciences to oral health and disease. Trainees can be individuals with a D.D.S., D.M.D., M.D., or equivalent degree, or pre- and post-Ph.D. It is essential that research training activities specifically apply informatics to areas pursued by the NIDR. These include: (1) the etiology, epidemiology, pathogenesis, prevention, diagnosis and treatment of dental caries, periodontal and oral soft tissue diseases, oral cancer, oral manifestations of AIDS and HIV infection, salivary gland conditions, craniofacial anomalies, orofacial pain, and temporomandibular disorders; (2) the molecular and cellular study of the development, structure and function of teeth, jaws, oral mucosa, bone, connective tissue, and salivary glands; (3) behavioral, social, cultural, economic, and health care delivery issues related to oral health and disease; (4) biomaterials, dental implants, biomimetics, and tissue engineering; (5) fluoride and nutrition; and (6) oral conditions prevalent among older Americans, a particular gender, minorities, people with particular systemic diseases, and other individuals and groups at high risk for oral health problems. The preparation of competent scientists remains the primary goal of the training program. However, NLM recognizes that informatics specialists are often called upon for assistance in addressing information needs of a health center, and strongly encourages program directors to provide trainees with some exposure to the problems of managing and integrating health enterprise information systems. Such training may be of particular interest to students whose traditional terminal degree is not a doctorate, but who desire a relevant doctoral degree. Training grant applications which include sponsors/preceptors who are requesting support in one or more of these enhancement areas will be subjected to the same peer review process as all other applications submitted in response to this RFA, and grants selected for an award will be administered by the NLM. Prospective applicants who have an interest in these special training tracks should declare their interest and focus that part of the application on areas that support relevant problem-solving topics. Support of training slots by other agencies will be based on the Initial Review Group's recommendation and priority score, relevance of the proposed project, program interests and the availability of funds. Institutions wishing to include the research experience gained by a trainee toward the research requirements of Board certification may do so at their discretion. Applications designed as preparation for certification in toto in medical specialties will not be acceptable. LETTER OF INTENT Prospective applicants are asked to submit by June 3, 1996, a letter of intent that includes a descriptive title of the proposed training, the name, address, telephone number and email address of the Training Director, the identities of other key personnel and participating institutions and the number and title of the RFA in response to which the application may be submitted. The letter of intent is requested in order to provide an indication of the number and scope of applications to be reviewed. The letter of intent is not binding, nor is it a requirement for submission of an application. The letter of intent is to be sent to: Roger W. Dahlen, Ph.D. Biomedical Information Support Branch National Library of Medicine Building 38A, Room 5S522 Bethesda, MD 20894 Telephone: (301) 496-4221 FAX: (301) 402-0421 Email: dahlen@lhc.nlm.nih.gov APPLICATION PROCEDURES Applications are to be submitted on research grant application PHS 398 (rev. 5/95). Beginning on page V-1 are instructions specific for institutional training grant applications. Applications kits are available at most institutional offices of sponsored research and may be obtained from the Grants Information Office, Office of Extramural Outreach and Information Resources, National Institutes of Health, 6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892-7910, telephone 301/710-0267, email: ASKNIH@odrockm1.od.nih.gov. In line 2 of the face page, applicants must clearly identify the application as a response to this RFA by entering the title, "Medical Informatics Research Training," and the RFA number. Attach the RFA label or a facsimile to the bottom of the face page of the original application. Send or deliver the completed application and five signed, exact photocopies to: DIVISION OF RESEARCH GRANTS NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710 BETHESDA, MD 20892-7710 BETHESDA, MD 20817 (for express/courier service) Applications must be received by June 19, 1996. The initial review group will meet in August, and the Board of Regents of the National Library of Medicine will conduct a final review in September. NLM will notify successful applicants about an intention to award shortly after the Board meeting. Although notification of intent to award cannot assure an award, only those so notified will be considered for funding. It is intended to issue awards with a July 1, 1997 begin date. In the administration of awards, the policies and requirements of the grant programs of the Public Health Service apply. REVIEW CONSIDERATIONS Upon receipt, applications will be reviewed for completeness by the NIH Division of Research Grants (DRG) and for responsiveness by NLM. Incomplete applications will be returned to the applicant without further consideration. Applications that are complete and responsive to the RFA will be evaluated for scientific and technical merit by an appropriate peer review group convened in accordance with the standard NIH peer review procedures. As part of the initial merit review, all applications will receive a written critique and undergo a process in which only those applications deemed to have the highest scientific merit, generally the top half of applications under review, will be discussed, assigned a priority score, and receive a second level review by the appropriate national advisory council or board. Review Criteria o past research training record for both the program and the designated preceptors in terms of the rate which former trainees establish independent and productive research careers o past research training record in terms of the success of former trainees in obtaining individual awards such as fellowships, career awards, FIRST awards, and research grants o objectives, design, and direction of the research training program o caliber of preceptors as researchers including successful competition for research support o training environment including the institutional commitment, the quality of the facilities, and the availability of research support o recruitment and selection plans for appointees and the availability of high quality candidates o the record of the research training program in retaining health- professional postdoctoral trainees for at least two years in research training or other research activities o the applicant's specific plans for the recruitment of individuals from under represented minorities and women. o the applicant's past record in selecting representatives from under represented groups and in training them for research programs. o a description of the formal or informal activities related to instruction about the responsible conduct of research that will be incorporated into the proposed research training program. AWARD CRITERIA Applications will compete for available funds with all other approved applications assigned to that IC. The following will be considered in making funding decisions: Quality of the proposed project as determined by peer review, availability of funds, and program priority. INQUIRIES Inquiries concerning this RFA are encouraged. The opportunity to clarify any issues or questions from potential applicants is welcome. Direct inquiries regarding programmatic issues to: Roger W. Dahlen, Ph.D. Biomedical Information Support Branch Extramural Programs National Library of Medicine Building 38A, Room 5S522 Bethesda, MD 20894 Telephone: 301-496-4221 FAX: (301) 402-0421 Email: dahlen@lhc.nlm.nih.gov Direct inquiries regarding grants management and fiscal matters to: Ms Ruth Bortz Extramural Programs National Library of Medicine Building 38A, Room 5N515 Bethesda, MD 20894 Telephone: (301) 496-4253 FAX: (301) 402-0421 Email: bortz@nes.nlm.nih.gov AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance, Medical Library Assistance, 13.879. Grants will be awarded under the authority of the Public Health Service Act, Section 472 (42 USC 286b-3) and administered under PHS grant policies and Federal Regulations, most specifically at 42 CFR Part 52 and 45 CFR Part 74. This program is not subject to review by a Health Systems Agency nor to the requirements of OMB Circular A-95. The PHS strongly encourages all grant and contract recipients to provide a smoke-free workplace and promote the non-use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people. .
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