NHLBI SHORT-TERM TRAINING FOR MINORITY STUDENTS PROGRAM (T35) RELEASE DATE: March 17, 2003 RFA: HL-03-014 (See replacement, RFA-HL-05-018) (see Notice of Additional Receipt Date, NOT-HL-04-015) National Heart, Lung, and Blood Institute (NHLBI) (http://www.nhlbi.nih.gov/) CATALOG OF FEDERAL DOMESTIC ASSISTANCE NUMBERS: 93.233, 93.837, 93.838, 93.839 LETTER OF INTENT RECEIPT DATE: May 22, 2003 APPLICATION RECEIPT DATE: June 23, 2003 (see NOT-HL-04-015) THIS RFA CONTAINS THE FOLLOWING INFORMATION o Purpose of this RFA o Research Objectives o Mechanism(s) of Support o Funds Available o Eligible Institutions o Individuals Eligible to Become Principal Investigators o Trainee Eligibility Requirements o Special Requirements o Where to Send Inquiries o Letter of Intent o Submitting an Application o Peer Review Process o Review Criteria o Receipt and Review Schedule o Award Criteria o Required Federal Citations PURPOSE OF THIS RFA The National Heart, Lung, and Blood Institute (NHLBI) Short-Term Training for Minority Students Program is a Ruth L. Kirschstein National Research Service Award (NRSA) designed to provide short-term research support to underrepresented minority undergraduate and graduate students and students in health professional schools to provide them with career opportunities in cardiovascular, pulmonary, hematologic and sleep disorders research. Underrepresented minority and ethnic groups include African Americans/Blacks, Hispanics, American Indians, Alaska Natives, and non-Asian Pacific Islanders and other racial and ethnic groups determined by the institutions to be underrepresented in the health-related sciences. The grant provides two to three consecutive months of research training with experienced investigators and exposes talented students to experiences that will help them pursue a biomedical or behavioral research career. In addition to the research experience, institutions provide enrichment activities such as research forums, guest lectures, student presentations, special courses, and social activities. RESEARCH OBJECTIVES This RFA is designed to offer research training opportunities for minority students in an effort to encourage them to participate in cardiovascular, pulmonary, hematologic, and sleep disorders research. The NHLBI Short-Term Training for Minority Students Program is intended to: o Provide minority undergraduate and graduate students and students in health professional schools with opportunities to participate in activities leading to research careers in areas relevant to cardiovascular, pulmonary, hematologic, and sleep disorders. o Attract qualified minority students into biomedical and behavioral research careers. o Increase the short supply of qualified minority investigators. Although the number of underrepresented minority individuals (Blacks, Hispanics, Native Americans) pursuing advanced degrees in the biomedical and behavioral sciences increased over the past 20 years, their representation in these fields remains below their representation in the U.S. population. During that time, both the number and percentage of science doctorates earned by underrepresented minorities have increased twofold. In 1997, however, the total of science doctoral degrees awarded to underrepresented minorities in these fields accounted for only 5.9 percent of the total degrees received (National Research Council, Survey of Earned Doctorates, 2000). Furthermore, in 1996, U.S. medical schools graduated more underrepresented minorities than ever and the number of minorities applying to medical school reached a new record high. A total of 5,259 minority students applied to the nation=s medical schools, representing 11 percent of all applicants (Association of American Medical Colleges, 1997). Yet, only 3.5 percent of all U.S. medical school faculty holding Ph.D. degrees in the biomedical and behavioral sciences, and only 3.6 percent of those with combined M.D./Ph.D. degrees are members of underrepresented minority groups. There are existing programs at the NIH that are designed to increase the number of minorities in biomedical and behavioral research. These include the NHLBI Minority Institutional Research Training Program, the NHLBI Mentored Minority Faculty Development Award, and the NHLBI Minority Institution Research Scientist Development Award. Even though these programs appear successful in meeting their specific objectives and career development goals, more needs to be done to attract minorities to biomedical and behavioral research careers. Although there is strong interest in the scientific community in attracting minority students into research careers, few minority students opt for science degrees and research careers, and few minority graduates of health professional schools go on to scientific research careers. The shortage of qualified minority investigators in academic research positions may even exacerbate the situation due to a lack of visible role models for students. One method of addressing this problem is by attracting minority students to research opportunities and by providing them with research training to develop their research capabilities in cardiovascular, pulmonary, hematologic, and sleep disorders. MECHANISM OF SUPPORT This RFA will use the Ruth L. Kirschstein NRSA Short-Term Research Training Grant (T35) award mechanism. Responsibility for the planning, direction, and execution of the proposed training project will be solely that of the applicant. The total project period for an application submitted in response to this RFA may not exceed five years. Funding beyond the first year of the grant is contingent upon satisfactory progress during the preceding year and availability of funds. The anticipated award date is April 1, 2004. FUNDS AVAILABLE The estimated funds (total costs) available for the first year of support for the entire program is expected to be $500,000 in Fiscal Year 2004 (October 1, 2003-September 30, 2004). The actual amount may vary, depending on the response to the RFA and availability of funds. Eight new awards are anticipated. Facilities and Administrative Costs – The Notice of Grant Award will provide facilities and administrative costs based on 8% of total direct costs. ELIGIBLE INSTITUTIONS Only domestic; for-profit and non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; units of State and local governments; and eligible agencies of the Federal government may apply for grants to support research training programs. The applicant institution must have a strong research program in the area(s) proposed for research training and must have the requisite staff and facilities to carry out the proposed program. Foreign institutions are not eligible to apply. INDIVIDUALS ELIGIBLE TO BECOME PRINCIPAL INVESTIGATORS/PROGRAM DIRECTORS Any individual with the skills, knowledge, and resources necessary to organize and implement a high quality research training program is invited to work with their institution as the director of the research training program in order to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH programs. The research training program director at the institution will be responsible for the selection and appointment of trainees to the NRSA research training grant and for the overall direction, management, and administration of the program. TRAINEE ELIGIBILITY REQUIREMENTS Trainees must have successfully completed at least one undergraduate year at an accredited school or university (including baccalaureate schools of nursing) or have successfully completed one semester at a school of medicine, optometry, osteopathy, dentistry, veterinary medicine, pharmacy, or public health, or an institution with an accredited graduate program, prior to participating in the program. Institutions must adhere strictly to these requirements when selecting trainees. These grants are intended to introduce students to research that would not otherwise be available through their regular course of studies. For graduate students, this may include graduate students in programs, such as mathematics and computer science, where they would not normally be exposed to biomedical research or minority graduate students who may need a specialized research experience to supplement their normal graduate education. Trainees appointed to this program must be citizens or non-citizen nationals of the United States or must have been lawfully admitted for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card I-551, or some other legal verification of such status). Noncitizen nationals are generally persons born in possessions of the United States (i.e., American Samoa and Swains Island). Individuals on temporary or student visas and individuals holding Ph.D., M.D., D.V.M. or equivalent doctoral degrees in the health sciences are not eligible. Trainees appointed to the program need not be from the applicant institution, but may include a number of underrepresented minority students from other institutions, schools, colleges, or universities. The program can be designed to include research experiences for minority individuals at the applicant institution but applicants are strongly encouraged to propose a program that includes a number of individuals from other institutions, schools, colleges or universities. The only requirement for student selection is that the trainees fulfill the above referenced eligibility requirements. SPECIAL REQUIREMENTS Provisions of the Award Institutions may request support for at least 4 but not more than 24 trainees per budget period, based on a full-time three-month appointment. A trainee may be appointed for a minimum of two months and a maximum of three months during a budget period; however, institutions are encouraged to appoint a trainee for more than one budget period, i.e., two or more successive summer research experiences. A student may be appointed, in special circumstances, to more than one 3-month period during a budget period, provided prior approval is obtained from the staff of the NHLBI. All research training must be full-time during the specific training sequence. It is expected that most programs will be designed to provide a summer research experience but other innovative program designs and time schedules will be considered. The requested number of short-term trainees must be justified in the application. Only one application per health professional school may be submitted for a given receipt date. Although a university may have more than one NHLBI Short- Term Training for Minority Students Program, they may not be in the same school. The applicant institution must have the available research facilities, personnel, and support for the program in the areas of cardiovascular, pulmonary, hematologic, or sleep disorders. Minority institutions with adequate staff and resources in these areas are encouraged to apply. These grants will support short-term research training experiences of consecutive two to three months' duration for minority undergraduate students, minority students in health professional schools, and minority graduate students. The grantee institution will determine which racial and ethnic groups are underrepresented in biomedical or behavioral research and will be responsible for the selection and appointment of trainees. Funds may be requested for: o Stipends - The current stipend level for trainees is $1,664 per month, and $54.71 per day. Stipends may be supplemented from non-Federal funds. o Training-related Expenses - Up to $183 per month per trainee may be requested yearly; and may be used for faculty, laboratory, and secretarial assistance; supplies and equipment; consultant costs; and tuition and fees. o Travel Expenses - The institution may request up to $500 per year per trainee to cover the cost of travel to and from the training institution. Institutions may request up to $750 per trainee if they expect that the majority of their trainees will be coming long distances (e.g., trainees coming from Puerto Rico and other distant sites), but must submit a strong justification for this need. The request will be subject to the Initial Review Group (IRG) and NHLBI review. Applicants may share travel costs among trainees so that the $500 allotted for a local trainee may be reprogrammed, without the NHLBI permission, to trainees needing higher cost reimbursement. The institution may also request up to $400 per month per trainee per diem or subsistence allowances while at the training site. o Facilities and Administrative Costs - The Notice of Grant Award will provide facilities and administrative costs based on 8% of total direct costs, exclusive of tuition, and fees. A Statement of Appointment form (PHS 2271, rev. 5/01) must be submitted at the start of each trainee appointment and reappointment. This form is available at the following URL address: http://grants.nih.gov/training/phs2271.pdf. Individuals supported under this program are not required to sign an NRSA Payback Agreement but must submit an NRSA Termination Notice. Training in the Responsible Conduct of Research (RCR): The application must include a description of plans to provide instruction in the responsible conduct of research. The Public Health Service policy on RCR (http://ori.hhs.gov/policies/RCR_Policy.shtml#rcr) describes nine core instructional areas that comprise RCR: data acquisition, management, sharing, and ownership; mentor/trainee responsibilities; publication practices and responsible authorship; peer review; collaborative science; human subjects; research involving animals; research misconduct; and conflict of interest and commitment. Plans for RCR training must describe the proposed subject matter, format, frequency and duration of instruction. No award will be made if an application lacks this component. See the NIH website http://www.nih.gov/sigs/bioethics for resources and information on this topic. WHERE TO SEND INQUIRIES We encourage inquiries concerning this RFA and welcome the opportunity to answer questions from potential applicants. Inquiries may fall into three areas: programmatic, review and financial or grants management issues: o Direct your questions about programmatic issues to: Michael Commarato, Ph.D. Division of Heart and Vascular Diseases (responding for all NHLBI programmatic Divisions) National Heart, Lung, and Blood Institute 6701 Rockledge Drive, MSC 7940 Bethesda, MD 20892-7940 Telephone: (301) 435-0530 FAX: (301) 480-1330 Email: commaram@nhlbi.nih.gov o Direct your questions about review issues to: Anne Clark, Ph.D. Chief, Review Branch Division of Extramural Affairs National Heart, Lung, and Blood Institute Two Rockledge Center, Room 7214 6701 Rockledge Drive, MSC 7924 Bethesda, MD 20892-7924 Bethesda, MD 20817 (for express mail) Telephone: (301) 435-0270 FAX: (301) 480-0730 Email: clarka@nhlbi.nih.gov o Direct your questions about financial or grants management matters to: Beckie Chamberlin Grants Management Specialist Division of Extramural Affairs National Heart, Lung, and Blood Institute 6701 Rockledge Drive, Room 7144, MSC 7926 Bethesda, MD 20892-7926 Telephone: (301) 435-0174 FAX: (301) 480-1948 Email: chamberr@nhlbi.nih.gov LETTER OF INTENT Prospective applicants are asked to submit a letter of intent that includes the following information: o A descriptive title of the proposed research o Name, address, and telephone number of the Program Director o Names of other key personnel o Participating institutions o Number and title of this RFA Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows NHLBI staff to estimate the potential review workload and plan for the review. The letter of intent is to be sent to Dr. Anne Clark at the address listed under WHERE TO SEND INQUIRIES by May 22, 2003. SUBMITTING AN APPLICATION Applications must be prepared using the PHS 398 research grant application instructions and forms (rev. 5/2001). The PHS 398 is available at http://grants.nih.gov/grants/funding/phs398/phs398.html in an interactive format. Refer to T section. For further assistance contact GrantsInfo, Telephone (301) 435-0714, Email: GrantsInfo@nih.gov. USING THE RFA LABEL: The RFA label available in the PHS 398 (rev. 5/2001) application form must be affixed to the bottom of the face page of the application. Type the RFA number on the label. Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. In addition, the RFA title (NHLBI SHORT-TERM TRAINING FOR MINORITY STUDENTS PROGRAM) and number (HL-03- 014) must be typed on line 2 of the face page of the application form and the YES box must be marked. The RFA label is also available at: http://grants.nih.gov/grants/funding/phs398/label-bk.pdf. SENDING AN APPLICATION TO THE NIH: Submit a signed, typewritten original of the application, including the Checklist, and three signed photocopies, in one package to: Center For Scientific Review National Institutes Of Health 6701 Rockledge Drive, Room 1040, MSC 7710 Bethesda, MD 20892-7710 Bethesda, MD 20817 (for express/courier service) All grant applications submitted to the Center For Scientific Review (CSR) must come via United States Postal Service or a recognized delivery/courier service. Individuals may not personally deliver packages to the building on Rockledge Drive. For further information please see http://grants.nih.gov/grants/guide/notice-files/NOT-OD-02-012.html. At the time of submission, two additional copies of the application and all five collated sets of the appendix material must be sent to Dr. Anne Clark at the address listed under WHERE TO SENDINQUIRIES. APPLICATION PROCESSING: Applications must be received by June 23, 2003. If an application is received after that date, it will be returned to the applicant without review. Although there is no immediate acknowledgement of the receipt of an application, applicants are generally notified of the review and funding assignment within 8 weeks. The Center for Scientific Review (CSR) will not accept any application in response to this RFA that is essentially the same as one currently pending initial review, unless the applicant withdraws the pending application. However, when a previously unfunded application, originally submitted as an investigator-initiated application, is to be submitted in response to an RFA, it is to be proposed as a NEW application. That is the application for the RFA must not include an Introduction describing the changes and improvements made, and the text must not be marked to indicate the changes. While the investigator may still benefit from the previous review, the RFA application is not to state explicitly how. PEER REVIEW PROCESS Upon receipt, applications will be reviewed for completeness by the CSR and responsiveness by the NHLBI. Incomplete and/or non-responsive applications will be returned to the applicant without further consideration. Applications that are complete and responsive to the RFA will be evaluated for scientific and technical merit by a Special Emphasis Panel in the Division of Extramural Affairs, NHLBI, in accordance with the review criteria stated below. As part of the initial merit review, all applications will: o Receive a written critique o Undergo a process in which only those applications deemed to have the highest scientific merit, generally the top half of the applications under review, will be discussed and assigned a priority score o Receive a second level review by the National Heart, Lung, and Blood Advisory Council. Review Considerations The application should provide a summary of the training program including its objectives, the types of research activities available, the faculty who will participate, the geographical area to be included in the recruitment, a mentoring plan, and any special activities or experiences to be provided to the trainees. It should also describe the administrative structure of the program and the distribution of responsibilities within it, plans for recruiting, selecting, and assigning trainees to research activities, duration of training and months in which it will occur, description of a typical student program including percent time to be spent in various activities, and additional support or services to be provided by the applicant institution. All applications must include a description of formal or informal activities or instruction related to the responsible conduct of research that will be incorporated into the proposed research training program. Applicants for competitive renewal applications will be required to provide information concerning past trainees in the program, the accomplishments of the program, trainee publications, and whether students supported by the program have pursued research careers. This information should also be included in the noncompeting renewal application. Therefore, it is important that the applicant includes plans for tracking students who participated in the program. REVIEW CRITERIA The following criteria will be considered when assessing the merits of the proposed NHLBI Short-Term Training for Minority Students Program. o Design of the proposed training program; o Qualifications, dedication, and previous training record of the program director and participating faculty, particularly with regard to prior experience with similar programs; o Adequacy of facilities, environment, and resources for the proposed research training; o Recruitment and selection plans for trainees, and the availability of high quality candidates; o Methods for retaining promising students in the program and methods for tracking students; o Commitment of the institution and participating faculty to the goals of the training program; and o Procedures for evaluation of the effectiveness of the program and the impact of the program on the students involved. ADDITIONAL REVIEW CRITERIA: In addition to the above criteria, your application will also be reviewed with respect to the following: PROTECTION OF HUMAN SUBJECTS FROM RESEARCH RISK: The involvement of human subjects and protections from research risk relating to their participation in the proposed research will be assessed. (See criteria included in the section on Federal Citations, below). INCLUSION OF WOMEN, MINORITIES AND CHILDREN IN RESEARCH: The adequacy of plans to include subjects from both genders, all racial and ethnic groups (and subgroups), and children as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects will also be evaluated. (See Inclusion Criteria in the section on Federal Citations, below). CARE AND USE OF VERTEBRATE ANIMALS IN RESEARCH: If vertebrate animals are to be used in the project, the five items described under Section f of the PHS 398 research grant application instructions (rev. 5/2001) will be assessed. o BUDGET: The reasonableness of the proposed budget and the requested period of support in relation to the proposed research. Training in the Responsible Conduct of Research: Every predoctoral and postdoctoral NRSA trainee supported by an institutional research training grant must receive instruction in the responsible conduct of research. (For more information on this provision, see the NIH Guide for Grants and Contracts, Volume 21, Number 43, November 27, 1992, see http://grants.nih.gov/grants/guide/notice-files/not92-236.html. Applications must include a description of a program to provide formal or informal instruction in scientific integrity or the responsible conduct of research. Applications without plans for instruction in the responsible conduct of research will be considered incomplete and will be returned to the applicant without review. o Although the NIH does not establish specific curricula or formal requirements, all programs are encouraged to consider instruction in the following areas: conflict of interest, responsible authorship, policies for handling misconduct, data management, data sharing, and policies regarding the use of human and animal subjects. Within the context of training in scientific integrity, it is also beneficial to discuss the relationship and the specific responsibilities of the institution and the graduate students or postdoctorates appointed to the program. o Plans must address the subject matter of the instruction, the format of the instruction, the degree of faculty participation, trainee attendance, and the frequency of instruction. o The rationale for the proposed plan of instruction must be provided. o Program reports on the type of instruction provided, topics covered, and other relevant information, such as attendance by trainees and faculty participation, must be included in future competing continuation and noncompeting applications. The NIH encourages institutions to provide instruction in the responsible conduct of research to all graduate students, postdoctorates, and research staff regardless of their source of support. NIH initial review groups will assess the applicant's plans on the basis of the appropriateness of topics, format, amount and nature of faculty participation, and the frequency and duration of instruction. The plan will be discussed after the overall determination of merit, so that the review panel's evaluation of the plan will not be a factor in the determination of the priority score. Plans will be judged as acceptable or unacceptable. The acceptability of the plan will be described in an administrative note on the summary statement. Regardless of the priority score, applications with unacceptable plans will not be funded until the applicant provides a revised, acceptable plan. Staff within the NIH awarding component will judge the acceptability of the revised plan. Following initial review, the NHLBI Advisory Council provides a second level of review. The Council will consider the assessment of the scientific and educational merit of the research training grant application as well the plan for instruction in the responsible conduct of research. RECEIPT AND REVIEW SCHEDULE Letter of Intent Receipt Date: May 22, 2003 Application Receipt Date: June 23, 2003 Peer Review Date: October/November 2003 Council Review: February 2004 Earliest Anticipated Start Date: April 1, 2004 AWARD CRITERIA Award criteria that will be used to make award decisions include: o Scientific and training merit (as determined by peer review) o Availability of funds o Programmatic priorities. REQUIRED FEDERAL CITATIONS HUMAN SUBJECTS PROTECTION: Federal regulations (45CFR46) require that applications and proposals involving human subjects must be evaluated with reference to the risks to the subjects, the adequacy of protection against these risks, the potential benefits of the research to the subjects and others, and the importance of the knowledge gained or to be gained. INCLUSION OF WOMEN AND MINORITIES IN CLINICAL RESEARCH: It is the policy of the NIH that women and members of minority groups and their sub-populations must be included in all NIH-supported clinical research projects unless a clear and compelling justification is provided indicating that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This policy results from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43). All investigators proposing clinical research should read the "NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research - Amended, October, 2001," published in the NIH Guide for Grants and Contracts on October 9, 2001 (http://grants.nih.gov/grants/guide/notice-files/ NOT-OD-02-001.html); a complete copy of the updated Guidelines are available at http://grants.nih.gov/grants/funding/women_min/ guidelines_amended_10_2001.htm. The amended policy incorporates: the use of an NIH definition of clinical research; updated racial and ethnic categories in compliance with the new OMB standards; clarification of language governing NIH-defined Phase III clinical trials consistent with the new PHS Form 398; and updated roles and responsibilities of NIH staff and the extramural community. The policy continues to require for all NIH-defined Phase III clinical trials that: a) all applications or proposals and/or protocols must provide a description of plans to conduct analyses, as appropriate, to address differences by sex/gender and/or racial/ethnic groups, including subgroups if applicable; and b) investigators must report annual accrual and progress in conducting analyses, as appropriate, by sex/gender and/or racial/ethnic group differences. INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS: The NIH maintains a policy that children (i.e., individuals under the age of 21) must be included in all human subjects research, conducted or supported by the NIH, unless there are scientific and ethical reasons not to include them. This policy applies to all initial (Type 1) applications submitted for receipt dates after October 1, 1998. All investigators proposing research involving human subjects should read the "NIH Policy and Guidelines" on the inclusion of children as participants in research involving human subjects that is available at http://grants.nih.gov/grants/funding/children/children.htm. PUBLIC ACCESS TO RESEARCH DATA THROUGH THE FREEDOM OF INFORMATION ACT: The Office of Management and Budget (OMB) Circular A-110 has been revised to provide public access to research data through the Freedom of Information Act (FOIA) under some circumstances. Data that are (1) first produced in a project that is supported in whole or in part with Federal funds and (2) cited publicly and officially by a Federal agency in support of an action that has the force and effect of law (i.e., a regulation) may be accessed through FOIA. It is important for applicants to understand the basic scope of this amendment. NIH has provided guidance at http://grants.nih.gov/grants/policy/a110/a110_guidance_dec1999.htm. Applicants may wish to place data collected under this RFA in a public archive, which can provide protections for the data and manage the distribution for an indefinite period of time. If so, the application should include a description of the archiving plan in the study design and include information about this in the budget justification section of the application. In addition, applicants should think about how to structure informed consent statements and other human subjects procedures given the potential for wider use of data collected under this award. URLs IN NIH GRANT APPLICATIONS OR APPENDICES: All applications and proposals for NIH funding must be self-contained within specified page limitations. Unless otherwise specified in an NIH solicitation, Internet addresses (URLs) should not be used to provide information necessary to the review because reviewers are under no obligation to view the Internet sites. Furthermore, we caution reviewers that their anonymity may be compromised when they directly access an Internet site. HEALTHY PEOPLE 2010: The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2010," a PHS-led national activity for setting priority areas. This RFA is related to one or more of the priority areas. Potential applicants may obtain a copy of "Healthy People 2010" at http://www.health.gov/healthypeople. AUTHORITY AND REGULATIONS: This program is described in the Catalog of Federal Domestic Assistance No. 93.233, 93.837, 93.838, and 93.839 and is not subject to the intergovernmental review requirements of Executive Order 12372 or Health Systems Agency review. Awards are made under authorization of Sections 301, 487, and 405 of the Public Health Service Act as amended (42 USC 241, 288, and 284) and administered under NIH grants policies described at http://grants.nih.gov/grants/policy/policy.htm and under Federal Regulations 42 CFR Parts 52 and 66 and 45 CFR Parts 74 and 92. The PHS strongly encourages all grant recipients to provide a smoke-free workplace and discourage the use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care, or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people.


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