RFA-HD-00-011: POPULATION RESEARCH INFRASTRUCTURE PROGRAM

Department of Health
and Human Services (HHS)

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POPULATION RESEARCH INFRASTRUCTURE PROGRAM Release Date: March 9, 2000 RFA: HD-00-011 National Institute of Child Health and Human Development Letter of Intent Receipt Date: August 15, 2000 Application Receipt Date: October 17, 2000 PURPOSE The National Institute of Child Health and Human Development (NICHD), through the Demographic and Behavioral Sciences Branch (DBSB), Center for Population Research (CPR), invites applications for infrastructure grants in support of population research relevant to the DBSB funding mission. Funds may be requested to support infrastructure and/or research designed to 1) enhance the quality and quantity of relevant research conducted at an institution, and 2) develop new research capabilities to advance population research through innovative approaches. A central goal of this program is to facilitate interdisciplinary collaboration and innovation in population research while providing essential and cost-effective core services in support of the development, conduct, and translation of relevant research based in population research centers or comparable administrative units. HEALTHY PEOPLE 2010 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of Healthy People 2010, a PHS- led national activity for setting priority areas. This RFA is related to several of the priority areas. Potential applicants may obtain Healthy People 2010 at http://www.health.gov/healthypeople/. ELIGIBILITY REQUIREMENTS Applications may be submitted by domestic, for-profit and non-profit organizations, public and private, such as universities, colleges, hospitals, laboratories, units of State and local governments, and eligible agencies of the Federal government. Foreign institutions are not eligible to apply. Racial/ethnic minority individuals, women, and persons with disabilities are encouraged to apply as Principal Investigators. Potential applicants are strongly encouraged to contact staff listed under INQUIRIES, below, to discuss eligibility prior to submission of an application. MECHANISM OF SUPPORT This RFA will use the National Institutes of Health (NIH) resource-related research project grant (R24) award mechanism. This mechanism is used to support projects that enhance the capabilities of resources to contribute to NIH extramural research. Responsibility for the planning, direction, and execution of the proposed project will be solely that of the applicant. NICHD expects to issue an RFA annually to solicit applications for this program, applications may be submitted only in response to an RFA. FUNDS AVAILABLE The NICHD intends to commit approximately $1,870,000 in total costs [Direct plus Facilities and Administrative (F & A) costs] in FY 2001 to fund three to six new and/or competing continuation grants in response to this RFA. Although the financial plans of the NICHD provide support for this program, awards pursuant to this RFA are contingent upon the availability of funds and the receipt of a sufficient number of meritorious applications. An applicant should request a total project period of five years. Because the nature and scope of the research proposed may vary, it is anticipated that the size of awards also will vary. Applicants should request support appropriate to the size and impact of their scientific portfolio and to the goals of their infrastructure program. As a general rule, for the purposes of this RFA, NICHD expects direct cost budget requests of approximately $150,000 for each 10 researchers in the program who can provide evidence of research activity relevant to the mission of DBSB in two or more of the following categories: (1) externally funded research grants or contracts in the past three years, (2) publications in peer-reviewed journals during the past three years, and/or (3) papers in preparation and future plans for research. See SPECIAL REQUIREMENTS, below, for further information on these categories of research activity. Requests may vary from this guideline as justified by evidence of exceptionally high impact or productivity or special features of the proposed infrastructure program. Applicants are encouraged to discuss budget requests with program staff listed under INQUIRIES, below, prior to submission. RESEARCH OBJECTIVES Background The Demographic and Behavioral Sciences Branch is one of three programs in the Center for Population Research of the National Institute of Child Health and Human Development. The mission of the Branch is to foster research on the processes that determine population size, growth, composition, and distribution, and on the determinants and consequences of those processes. This mission translates into a research portfolio that looks intensively at the demographic processes of fertility, mortality, and migration and at their broad interrelationships with larger social, economic, and cultural processes. Areas of supported research include fertility and family planning, sexually transmitted disease, family and household demography, mortality and health, population movement, and population composition and change. Relevant research can cover a broad spectrum of scientific approaches in the clinical, behavioral, and social sciences. Since 1972, NICHD has been providing infrastructure support for population research through the Center Core Grant (P30) and Specialized Research Center Grant (P50) mechanisms. In 1999, NICHD undertook a comprehensive review of this program to determine whether its structure and guidelines best served the future needs of population research. A report summarizing the results of this review is available at http://www.nichd.nih.gov/about/cpr/dbs/pubs/report.pdf and from the program contact named under INQUIRIES. As a result of the review, NICHD will phase out the P30 and P50 mechanisms in favor of the Infrastructure Grant (R24) for purposes of providing support for the development of infrastructure for population research. Objectives and Scope The primary purposes of the Population Research Infrastructure Program are to provide resources for research that will improve the understanding of the antecedents and consequences of population structure and change, facilitate interdisciplinary collaboration among investigators conducting population- related research, and promote innovative approaches to population research questions. An additional goal is to facilitate interaction among scientists in locations throughout the United States to contribute to the integration and coordination of population research. The Infrastructure Grant will retain some of the characteristics of traditional P30 and P50 grants. It will continue to provide infrastructure to support a portfolio of relevant research at an institution. However, it is designed to move beyond the traditional center grant mechanism to allow institutions to aggressively pursue scientific opportunities that are appearing at the boundaries between traditional population research and allied fields, and to facilitate partnerships among diverse scientists and institutions. The Infrastructure Grant replaces the cost accounting approach required in the traditional P30 grant with a streamlined format that allows more flexible use of funds to address not only the core support needs of existing projects, but also the development of new directions and approaches to population research and the translation of research findings. Projects and themes proposed in applications responding to this RFA must be relevant to the DBSB funding mission. A description of the DBSB mission is available at http://www.nichd.nih.gov/about/cpr/dbs/dbs.htm. Examples of relevant population research topics are listed below and applicants may concentrate on any combination of relevant topics. Applicants are encouraged to consult with program staff listed under INQUIRIES to determine the relevance of other topics to the DBSB funding mission. The following examples are to be considered illustrative: 1. Antecedents and consequences of changes in population size, structure, and composition, including the relationship of economic development to population growth and decline, population modeling and the projection and/or prediction of human population change, the interrelationship between population and the physical environment. 2. Family and household dynamics, including issues related to intergenerational relationships. 3. Fertility and family planning, including issues related to union formation and dissolution, births and birth spacing, family size, gender in relation to fertility, social acceptability of measures for the biological regulation of human fertility. 4. Causes and consequences of migration of human population groups, including issues related to international migration, internal spatial distribution. 5. Demographic aspects of health, morbidity, disability, and mortality, including issues related to the influence of early life on later life development and outcomes, status of children, the interrelationship between health and socioeconomic status. 6. Social, demographic, and behavioral studies of sexual behavior, sexually transmitted diseases, and contraception. Categories of Infrastructure Support Applicants may request support in the following categories: Research Support Cores, Developmental Infrastructure, Translational Cores, Cooperative Infrastructure, and Research Projects. Applicants are not expected to request support in all or even most of the categories. The types and amounts of support requested must be justified in terms of the scope, objectives, and impact of the program, the potential contribution of requested support for advancing the research program, and the cost- effectiveness of the requested support in addressing the goals of this RFA. Applicants are expected to define guidelines for determining the eligibility of researchers and research projects to access resources provided under this program, and guidelines and procedures for allocating such resources. No restrictions on access (e.g., by students, investigators lacking research support, investigators in fields other than population research, etc.) are imposed under this announcement. However, the guidelines and procedures proposed by applicants for controlling access must be justified in terms of their effectiveness in meeting the goals of this RFA. o Research Support Cores provide shared resources in support of a significant portfolio of relevant population research. Examples include: Administrative Core, providing for coordination of research, editorial services, and/or assistance with grant application development and fiscal management of grants. Computing Core, providing equipment and/or services in support of shared computing needs. Information Core, providing support for the retrieval of various types of information resources commonly used in population research, such as published materials and data. Cores providing support for specific methodologies employed in population research (e.g., GIS, statistical methods, biomarkers, survey methodologies). Equipment and support services that are specific to individual research projects or researchers are not allowable, except in the context of individual research projects that may be proposed. Applicants also may request up to $50,000 in direct costs annually to support coordination activities that will promote communication, dissemination, and/or cost-efficiencies among centers of population research, including at a minimum all those units funded under this announcement and existing P30/P50 Population Research Centers. Examples of potential activities include development of a central website, management of a listserve, organization of conferences focused on research or issues of concern to population centers, and clearinghouse-type activities to promote access to and dissemination of scarce research resources. o Developmental Infrastructure refers to activities that promote the development of new research capabilities. Examples include: Seed grant programs, providing funds for the development of new research projects. Institutions proposing seed grant programs must develop guidelines and eligibility requirements appropriate to the goals of this RFA, and procedures for administration and peer review of the program. Faculty development, providing for partial or full salary support or other support for the recruitment of new faculty in scientific areas critical to the development of innovative and/or interdisciplinary research directions. Support for any one individual may not exceed three years in duration. Activities that foster the development of new core services. For example, applicants may propose consulting services to assist with the design of GIS services, or conduct pilot studies to test alternative modes of delivery of existing services for cost-effectiveness. Workshops, conferences, seminar series, and visiting scholar programs that lay the groundwork for new substantive work or foster new research collaborations. o Translational Cores may provide support for public use access to large data collection projects and/or outreach efforts to elucidate the clinical or public policy implications of research. Examples include data enclaves that permit use of restricted data in secure settings and summaries of research that are targeted to non-research audiences. o Cooperative Infrastructure refers to activities to develop research partnerships involving scientists in the applicant’s program and colleagues in other institutions, and/or joint ventures with other institutions to provide research, developmental, or translational services to researchers. Proposed research partnerships must be justified in terms of the scientific advances to be gained through collaborations across institutions relative to those likely to emerge from within-institution partnerships. Examples of allowable activities include travel for project development and coordination and use of research support core, seed project, and research project funds. Applicants also may propose cooperative research support, developmental, or translational services in which the applicant and a Population Center or similar unit in another institution participate in joint funding and administration of a common service or resource. Examples might include a shared library, data archive, or outreach effort. Partners in a cooperative venture need not be another funded applicant or Center. Applicants must clearly describe the rights and responsibilities of each proposed partner in the funding, administration, and use of shared resources. o Research Projects proposed must directly embody and advance the program’s core or signature scientific objectives and should emphasize innovative, interdisciplinary, and/or cross-cutting elements. Institutions are encouraged to consider R01 and other research grant mechanisms for the support of research projects that do not explicitly meet these criteria. SPECIAL REQUIREMENTS Applicant institutions must have an established research center or other administrative unit (hereafter referred to as the unit ) that serves as a focal point for or coordinates population research across the institution. This unit must have a defined governance structure. The Principal Investigator should be a scientist or science administrator who can provide effective administrative and scientific leadership. The research program conducted at the unit should reflect scientific benefits and cost- efficiencies resulting from cooperation and interaction among a pool of scientists with shared interests in population research. To be eligible to apply, the unit must have at least three researchers who can present evidence of research activity related to the mission of DBSB in all three of the following categories: (1) externally funded research grants or contracts in the past three years, (2) publications in peer-reviewed journals during the past three years, (3) papers in preparation and future plans for research. The past three years refers to the 36-month period preceding the application submission date for this RFA. Externally funded means funding is received from sources outside the institution, it may include funding from NIH, NSF, other federal agencies, state and local governments, and private foundations. Include only projects on which the individual has served as Principal Investigator or had substantial involvement, comparable to that indicated by identification of an investigator as key personnel on an NIH-funded grant. Note that the criterion used for eligibility above (at least three researchers with evidence of research activity in all three categories) differs from the criteria used to define guidelines for requested budgets under FUNDS AVAILABLE and to define page limitations under APPLICATION PROCEDURES - C. RESEARCH ACTIVITY. In each of the latter two cases, the criterion of an active researcher is evidence of research activity in at least two of the three categories defined above. In addition, because the Infrastructure Program is expected to enhance the unit’s competitiveness for NIH funding, the institution and pertinent departments are expected to show a strong commitment to the unit and matching the requested infrastructure support at a level appropriate to the resources of the institution and the scope of the proposed program activities. Such commitment may be demonstrated by the provision of dedicated space, faculty appointments in subject areas relevant to the goals of the program, salary support for investigators or core staff, dedicated equipment, or other financial support for the proposed program. Applicants are encouraged to consult with program staff listed under INQUIRIES to discuss this requirement. INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS It is the policy of the NIH that women and members of minority groups and their subpopulations must be included in all NIH supported biomedical and behavioral research projects involving human subjects unless a clear and compelling rationale and justification are provided that inclusion is inappropriate with respect to the health of the subjects or the purpose of the research. This policy results from the NIH Revitalization Act of 1993 (Section 492B of Public Law 103-43). All investigators proposing research involving human subjects should read the NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical Research, published in the Federal Register of March 28, 1994 (59 FR 14508- 14513) and in the NIH Guide for Grants and Contracts, Volume 23, Number 11, March 18, 1994, and available at: http://grants.nih.gov/grants/guide/notice-files/not94-100.html. INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS It is the policy of NIH that children (i.e., individuals under the age of 21) must be included in all human subjects research, conducted or supported by the NIH, unless there are scientific and/or ethical reasons not to include them. This policy applies to all initial (Type 1) applications submitted for receipt dates after October 1, 1998. All investigators proposing research involving human subjects should read the NIH Policy and Guidelines on the Inclusion of Children as Participants in Research Involving Human Subjects, published in the NIH Guide for Grants and Contracts, March 6, 1998, and available at: http://grants.nih.gov/grants/guide/notice-files/not98-024.html. Investigators also may obtain copies of these policies from the program staff listed below under INQUIRIES. LETTER OF INTENT Prospective applicants are asked to submit a letter of intent that includes a descriptive title of the proposed research, the name, address, and telephone number of the Principal Investigator, the identities of other key personnel and participating institutions, and the number and title of this RFA. Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows NICHD staff to estimate the potential review workload and avoid conflict of interest in the review. The letter of intent is to be sent to Dr. Christine Bachrach at the address listed under INQUIRIES, below, by August 15, 2000. URLs IN NIH GRANT APPLICATIONS OR APPENDICES All applications and proposals for NIH funding must be self-contained within specified page limitations. Unless otherwise specified in an NIH solicitation, internet addresses (URLs) should not be used to provide information necessary to the review because reviewers are under no obligation to view the Internet sites. Reviewers are cautioned that their anonymity may be compromised when they directly access an Internet site. APPLICATION PROCEDURES The research grant application form PHS 398 (rev. 4/98) is to be used in applying for these grants. These forms are available at most institutional offices of sponsored research, on the Internet at http://grants.nih.gov/grants/funding/phs398/phs398.html, and from the Division of Extramural Outreach and Information Resources, National Institutes of Health, 6701 Rockledge Drive, MSC 7910, Bethesda, MD 20892- 7910, telephone 301-710-0267, E-mail: Grantsinfo@nih.gov. Application Instructions Applications for the Population Research Infrastructure Program (R24) grant should be prepared according to the Application Guidelines available at http://www.nichd.nih.gov/rfa/hd-00-011/hd-00-011.htm and from program staff listed under INQUIRIES. All instructions and guidelines accompanying the PHS 398 are to be followed, with the exception of the sections modified by these guidelines. Submission Instructions The RFA label available in the PHS 398 application form must be stapled to the bottom of the face page of the application and must display the RFA number HD-00-011. A sample RFA label is available at http://grants.nih.gov/grants/funding/phs398/label-bk.pdf. Please note this is in the pdf format. Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. In addition, the RFA title ( Population Research Infrastructure Program ) and number (HD-00-011) must be typed on line 2 of the face page and the YES box must be marked. Submit a signed typewritten original of the application, including the checklist, and three signed photocopies, in one package to: CENTER FOR SCIENTIFIC REVIEW NATIONAL INSTITUTES OF HEALTH 6701 ROCKLEDGE DRIVE, ROOM 1040, MSC 7710 BETHESDA, MD 20892-7710 BETHESDA, MD 20817 (for express/courier service) At the time of submission, two additional copies of the application should be sent to: L. R. Stanford, Ph.D. Division of Scientific Review National Institute of Child Health and Human Development 6100 Executive Boulevard, Room 5E01, MSC 7510 Bethesda, MD 20892-7510 Rockville, MD 20852 (for express/courier service) Applications must be received by October 17, 2000. If an application is received after that date, it will be returned to the applicant without review. The Center for Scientific Review (CSR) will not accept any application in response to this RFA that is essentially the same as one currently pending initial review, unless the applicant withdraws the pending application. The CSR will not accept any application that is essentially the same as one already reviewed. This does not preclude the submission of substantial revisions of applications already reviewed, but such applications must include an introduction addressing the previous critique. REVIEW CONSIDERATIONS Upon receipt, applications will be reviewed for completeness by the CSR and for responsiveness to this RFA by the NICHD. Incomplete and/or non- responsive applications will be returned to the applicant without further consideration. Applications that are complete and responsive to the RFA will be evaluated for scientific and technical merit by an appropriate peer review group convened by the NICHD in accordance with the review criteria stated below. Although site visits may be conducted in selected cases, applicants should anticipate that no site visit will be conducted and ensure that their applications are complete at the time of submission. As part of the initial merit review, all applications will receive a written critique and may undergo a process in which only those applications deemed to have the highest scientific merit will be discussed, assigned a priority score, and receive a second level review by the National Advisory Child Health and Human Development Council. Review Criteria Overall Program: Five primary criteria will be used to evaluate the overall scientific merit of an application for the Population Research Infrastructure Program. o Quality of the scientific program and its impact on the field: Reviewers will consider the significance, innovation, and quality of current and recent contributions of program scientists. Have these contributions resulted in the production of new knowledge and/or new approaches to research that have significantly expanded, improved or altered the content, methods, and direction of population research? o Quality and potential impact of proposed infrastructure program: Reviewers will examine the overall quality, scientific merit, and innovation of the activities to be supported. Reviewers will consider the likelihood that, based on existing capabilities and proposed activities, the proposed program will enhance population research, promote new research directions, facilitate interactions across disciplines and substantive areas of study, and advance theoretical or technical approaches. o Research competence of key personnel: Reviewers will consider the capability and scientific credentials of the Principal Investigator to direct the Program and maintain high standards of research collaboration, the specific technical qualifications of core directors, and the scientific accomplishments of all participating investigators. o Institutional commitment and environment: The nature and level of resource commitment from the institution in which the center is housed and any cooperating institutions. Institutional commitment will be evaluated relative to the institutional context. Reviewers also will consider the academic and physical environment as it bears on research opportunities, space, equipment, and the potential for interaction with scientists from various departments, institutions or disciplines. o Cost-efficiency of proposed infrastructure program in relation to the goals of this RFA. Infrastructure Support Components: Individual elements of the proposed infrastructure program, including Research Support Cores, Developmental Infrastructure, Translational Cores, and Cooperative Infrastructure, will be evaluated separately with respect to their contribution to enhancing the productivity of the existing scientific program, fostering new scientific opportunities, and enhancing the impact of unit research. Review criteria applicable to all to categories of infrastructure support are: o appropriateness to the size and characteristics of the existing scientific portfolio and the goals of the program, o potential or actual contribution of the proposed core or activity to advancing research within and/or beyond the applicant unit, o quality and cost-effectiveness of services or activities, o qualifications, experience, and commitment to the program of the investigators responsible for the core units or activities and their ability to devote the required time and effort to the program, o appropriateness given other sources of support within the institution and center, and o appropriateness of the budgetary requests. In addition, the following criteria will be applied to specific types of infrastructure support: o For seed grant programs proposed under Developmental Infrastructure, the appropriateness and quality of program guidelines and provisions for a competitive, peer-reviewed, allocation of funds. Upon renewal, seed grant programs will be reviewed for their success in developing funded research projects relevant to the mission of DBSB. o For Translational Cores, the significance of the proposed activity, its potential for the dissemination of population research and data and/or the translation of research into clinical applications and policy-relevant information tools. o For Cooperative Infrastructure, the value added to the scientific program of the center by the involvement of other institutions, the appropriateness and adequacy of plans for the sharing of rights and responsibilities among proposed partners with respect to the funding, administration, and use of shared resources. o For applications proposing coordination activities as defined under Categories of Infrastructure Support, the potential of the proposed activities for promoting communication, dissemination, and/or cost- efficiencies among centers of population research. Research Projects: The goals of NIH-supported research are to advance our understanding of biological systems, improve the control of disease, and enhance health. In the written comments, reviewers will be asked to discuss the following aspects of each project in order to judge the likelihood that the proposed research will have a substantial impact on the pursuit of these goals. Each of the criteria listed below will be addressed and considered in assigning the score for a research project, weighting them as appropriate for each project. Note that the project does not need to be strong in all categories to be judged likely to have major scientific impact and thus deserve a high priority score. For example, an investigator may propose to carry out important work that by its nature is not innovative but is essential to move a field forward. (1) Significance. Does this study address an important problem? If the aims of the application are achieved, how will scientific knowledge be advanced? What will be the effect of these studies on the concepts or methods that drive this field? (2) Approach. Are the conceptual framework, design, methods, and analyses adequately developed, well-integrated, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics? (3) Innovation. Does the project employ novel concepts, approaches or method? Are the aims original and innovative? Does the project challenge existing paradigms or develop new methodologies or technologies? (4) Investigator. Is the investigator appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the Principal Investigator and other researchers (if any)? (5) Environment. Does the scientific environment in which the work will be done contribute to the probability of success? Do the proposed experiments take advantage of unique features of the scientific environment or employ useful collaborative arrangements? Is there evidence of institutional support? In addition, each proposed research project will be evaluated with respect to: o the contribution of the project to advancing the unit’s core or signature scientific objectives and the extent to which it embodies innovative, collaborative, and/or cross-cutting elements of the unit. In addition to the above criteria, in accordance with NIH policy, all individual scientific projects will be reviewed with respect to the following: o The adequacy of plans to include both genders, minorities and their subgroups, and children as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects also will be evaluated. o The reasonableness of the proposed budget and duration in relation to the proposed research. o The adequacy of the proposed protection for humans, animals or the environment, to the extent they may be adversely affected by the project proposed in the application. SCHEDULE Letter of Intent Receipt Date: August 15, 2000 Application Receipt Date: October 17, 2000 Peer Review Date: April 2001 Council Review: June 2001 Earliest Anticipated Start Date: July 1, 2001 AWARD CRITERIA Applications will compete for available funds with all other applications that are submitted in response to this RFA. Selection of applications for award, and the levels of support provided, will be based on 1) scientific and technical merit of the proposed project and components as determined by peer review, 2) program priorities and program balance, and 3) availability of funds. Within applications recommended for funding, specific infrastructure components may be funded selectively. INQUIRIES Inquiries concerning this RFA are encouraged. The opportunity to clarify any issues or respond to questions from potential applicants is welcome. Researchers considering an application in response to this RFA are strongly encouraged to discuss their ideas with DBSB staff in advance of formal submission. Direct inquiries regarding programmatic issues to: Dr. Christine Bachrach Demographic and Behavioral Sciences Branch, CPR National Institute of Child Health and Human Development 6100 Executive Boulevard, Room 8B07, MSC 7510 Bethesda, MD 20892-7510 Rockville, MD 20852 (for express/courier service) Telephone: (301) 496-9485 FAX: (301) 496-0962 Email: cbachrach@nih.gov (email communication preferred) Direct inquiries regarding fiscal and administrative matters to: Ms. Mary Ellen Colvin Grants Management Branch National Institute of Child Health and Human Development 6100 Executive Boulevard, Room 8A17G, MSC 7510 Bethesda, MD 20892-7510 Telephone: (301) 496-1304 Email: mc113b@nih.gov AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance No. 93.864 (Population Research). Awards made are under authorization of Sections 301 and 405 of the Public Health Service Act, as amended (42 USC 241 and 284) and administered under NIH grant policies and Federal Regulations, 42 CFR Part 52 and 45 CFR Parts 74 and 92. This program is not subject to the intergovernmental review requirements of Executive Order 12372 or to Health Systems Agency review. The PHS strongly encourages all grant and contract recipients to provide a smoke-free workplace and promote the non-use of all tobacco products. In addition, Public Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain facilities (or in some cases, any portion of a facility) in which regular or routine education, library, day care, health care, or early childhood development services are provided to children. This is consistent with the PHS mission to protect and advance the physical and mental health of the American people.

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