Full Text DE-94-001 REGIONAL RESEARCH CENTERS FOR MINORITY ORAL HEALTH: PHASE II NIH GUIDE, Volume 23, Number 1, January 7, 1994 RFA: DE-94-001 P.T. 04, FF Keywords: Oral Diseases Dentistry National Institute of Dental Research National Center for Research Resources Letter of Intent Receipt Date: March 15, 1994 Application Receipt Date: September 21, 1994 PURPOSE The National Institute of Dental Research (NIDR) and the Research Centers in Minority Institutions (RCMI) Program of the National Center for Research Resources (NCRR) invite applications for grants for Phase II of the Regional Research Centers for Minority Oral Health (RRCMOH) initiative. Receipt of a Phase I grant is not a prerequisite for submission of an application for a Phase II grant. The objective of the RRCMOH initiative is to improve the oral health of U.S. racial and ethnic minorities, to expand the research opportunities for minority scientists by encouraging their participation in oral health research, and to develop and strengthen the biomedical and behavioral oral health research capacity of minority dental schools and RCMI eligible institutions. For the purpose of this solicitation, African Americans, Hispanics, Asians, Pacific Islanders, and Alaskan Natives are considered to be racial or ethnic minorities. An orientation meeting for potential applicants will be conducted by NIDR and NCRR/RCMI extramural program staff in connection with the annual meeting of the American Association for Dental Research, in March 1994, in Seattle, Washington. Details of the time and location of the meeting are available from the NIDR staff listed under INQUIRIES. HEALTHY PEOPLE 2000 The Public Health Service (PHS) is committed to achieving the health promotion and disease prevention objectives of "Healthy People 2000," a PHS-led national activity for setting research priority areas. This Requests For Applications (RFA), Regional Research Centers for Minority Oral Health: Phase II, is related to the priority area of reducing health disparities among Americans by improving oral health. Potential applicants may obtain a copy of "Healthy People 2000" (Full Report: Stock No. 017-001-00474-0) or "Healthy People 2000" (Summary Report: Stock No. 017-001-00473-1) through the Superintendent of Documents, Government Printing Office, Washington, DC 20402-9325 (telephone 202-783-3238). ELIGIBILITY REQUIREMENTS Only minority dental schools and dental schools serving large minority populations are eligible to submit applications in response to this request. Prior receipt of a Phase I grant is not a prerequisite for applying for, or receiving, a Phase II grant. Applications from foreign institutions or those involving foreign collaborations are not eligible. To be responsive to this RFA, an applicant must propose collaborative affiliations with other institutions that conform to the following organizational structures and that address the objectives of the RRCMOH initiative o A minority dental school must propose an affiliation with one or more research intensive dental schools. In addition, this arrangement may include affiliations with one or more minority institutions. Applications proposing affiliations between minority institutions without substantive involvement of research intensive institutions are not acceptable. o A research intensive dental school serving a large minority population must propose an affiliation with one or more research-intensive institutions and additionally may include an affiliation with one or more minority institutions. o A research intensive institution may not be the applicant organization unless it serves a large minority population. In instances where a dental school that serves a large minority population also qualifies as a research-intensive institution, affiliations must still be proposed with one or more minority institutions. When a minority dental school is not the applicant institution, clear evidence of substantive involvement by the minority dental school or minority institution in center activities must be provided. Regional proximity of the affiliated institutions may be an asset but, for a variety of reasons, such an arrangement may not be possible. In those instances, applicants are urged to provide compelling evidence of procedures and/or processes that will be used to overcome any potential problems associated with the geographical separation. Definitions The following definitions are used for the purpose of this RFA: 1. "minority dental school" - a school whose student enrollment and faculty consists of 50 percent or more ethnic minorities; 2. "dental school serving large minority populations" - a dental school whose patient population consists of 50 percent or more ethnic minorities; and 3. "research intensive institution" - an institution that received at least one million dollars of NIDR research and training funds during Fiscal Year 1993. A list of these institutions is provided as an appendix to this RFA; and 4. "minority institution" - an educational, health care or research institution staffed predominantly by ethnic minorities, renders service predominantly to minority groups, and/or whose student population consists primarily of individuals from minority groups. MECHANISM OF SUPPORT This RFA is a one time solicitation by the NIDR and the NCRR/RCMI, unless it is determined that there is a continuing program need. Under Phase II of the RRCMOH initiative, awards will be for up to five years using the Specialized Center (P50) mechanism. The earliest possible date for funding is September 1, 1995. Responsibility for the planning, direction and execution of the proposed research will be solely that of the applicant and collaborating institutions. However, periodic consultation with NIDR and NCRR/RCMI staff may be expected in the form of periodic site visits and/or meetings of center directors. FUNDS AVAILABLE It is anticipated that up to three, five-year awards may be made if a sufficient number of highly meritorious applications are received. Each award may not exceed $500,000 in direct costs for research projects, pilot projects and cores for the first year. Additional support of up to $100,000 in direct costs for the first fiscal year may be provided by the NCRR/RCMI program for RRCMOH-related faculty development activities where the applicant institution meets the basic RCMI eligibility criteria (i.e., more than 50 percent minority students and awards, M.D., D.D.S., Ph.D. or other relevant health science degrees). However, where indirect costs are assigned to a subcontract and counted as direct costs on the parent grant, the allowable direct cost maximum may be exceeded by the amount of the indirect costs assigned to the subcontract. Increases in costs for subsequent years, including those for faculty development, will not exceed four percent. It is strongly urged that additional funds be sought from institutional, corporate and foundation sources to augment support from the NIDR. Award of grants pursuant to this RFA is contingent upon the availability of funds. RESEARCH OBJECTIVES Background The NIDR, along with NCRR through the RCMI program, in recognizing the need to improve the oral health status of minorities relative to other groups, launched the RRCMOH initiative in September 1992. At that time, awards were made to six centers whose hallmark was collaboration between minority institutions and research intensive institutions committed to achieving the objectives of the program. The three year developmental grants were aimed at providing minority institutions with the opportunity to establish affiliations and organizational structures which could facilitate research on dental and oral health problems, particularly those of importance to minority populations. In initiating the RRCMOH program, the NIDR and the NCRR responded to evidence that shows that, on most measures of oral health, ethnic minorities are worse off than their counterparts in mainstream U.S.A. For example, while over half of all children between 5 and 17 years have no cavities in their permanent teeth, there are still substantial disparities in the application of known caries preventive strategies in minority populations, particularly among those who may not have access to dental and other health promotion services. The disparity in oral health between minority and other populations in the United States is highlighted in the NIDR Long-Range Research Plan for the Nineties, BROADENING THE SCOPE, a plan that calls for addressing all diseases affecting the oral cavity among all populations and at all ages. The development of the plan was aided by conceptual contributions from participants in dental and oral health research including minorities, who emphasized the need for consortial arrangements to strengthen the capacity of minority institutions to plan and conduct scientifically meritorious research and to engage in appropriate research training and career development. In addition, emphasis was placed on social and behavioral sciences in order to encourage the development of culturally sensitive strategies to effect disease prevention and health promotion behaviors. The necessity for a concerted effort in achieving the three major objectives of the RRCMOH initiative is based on the rapidly increasing number and diversity of minorities in the U.S. population and the generally poor status of oral health among minority populations. The oral health status of African Americans, for example, is compromised when assessed by virtually every oral health parameter (e.g., incidence and prevalence of caries, missing teeth, gingivitis/periodontitis and oral malignancies). Another indicator of the need for additional research on minority populations is the fact that the information available for other minority groups is too limited to allow valid comparisons on most oral health measures. Anecdotal reports of the status of these groups, however, indicate that they may be even more disadvantaged than African Americans. While a recent survey indicated that there are significant differences in oral health among different groups of Hispanic Americans, more specific information about the oral health status of Hispanics in the United States is similarly sparse. The relatively poor oral health status of minority populations as well as the lack of research on these conditions may reflect the relative scarcity of minority scientists engaging in basic and clinical oral health research. This may be attributed to limited opportunities for minorities to participate in research activities. While the NIDR continues to encourage the participation of minority scientists in oral health research through various training programs as well as through the recently established Research Supplements for Underrepresented Minorities initiative, the ability to conduct large-scale studies is often dependent on substantial external funding. The ability to obtain such support, especially from the Federal government, is, in turn, often dependent on a successful record of previous research and on a research infrastructure capable of supporting proposed research projects as well as on the inherent scientific merit of the projects. Without the opportunity to establish such a research record or to develop the necessary resources to support research, qualified scientists at minority institutions are often disadvantaged when compared with their colleagues at research intensive institutions. Thus, a central aim of the RRCMOH program is to enhance the funding opportunities for scientists at minority institutions by pairing them, through collaborative affiliations, with individuals at research intensive institutions who have both the resources and experiences necessary to successfully compete in the NIH scientific peer review system. It is anticipated that accomplishment of this aim will not only enhance the research careers of minority scientists but also attract qualified minority undergraduate and graduate students to careers in dental and oral health research. Center Characteristics Each center will be a consortium consisting of two or more institutions, as described under ELIGIBILITY REQUIREMENTS. The consortium will be structured to foster an alliance capable of addressing the objectives of the RRCMOH initiative. A director, affiliated with the applicant institution, and a co-director, affiliated with the principal collaborating institution, will be responsible for the scientific and administrative leadership of the center. The director will be assisted by an administrative advisory committee of senior staff from the principal participating institutions. Membership on this committee may be supplemented as needed by individuals from outside the participating institutions. The role of this committee is to provide administrative advice to the director by assisting in the preparation of the application, advising the director on scientific and related issues including faculty development activities. In addition, an independent scientific advisory committee consisting of consultants with appropriate research experience and accomplishments, but who are not associated with the participating institutions, will aid in the review of pilot projects proposed after initiation of the grant. This committee will also assess interim progress of all scientific projects and their relevance to the broad objectives of the RRCMOH initiative. The center will consist of a series of related research projects and cores focusing on the oral health of minorities. The projects may be of a pilot nature or they may be regular research projects. Each project will involve participation by co-investigators from the collaborating institutions. It is expected that each center will support a minimum of three regular research projects and no more than five pilot projects. Projects involving outreach to minority populations are encouraged. Some may involve basic biomedical or behavioral research while others may be drawn from the clinics and the catchment area of the minority dental school or of the dental school serving a large minority population. Core resources such as center development activities, administrative services, unique clinical facilities, animal facilities, biostatistical and computer services, and shared equipment will be supported. The level of support for core resources should be commensurate with the level of research proposed and funded. The center administrative core might include support of meetings or other activities to explore new and expanded collaborative research, research training, and career development opportunities. Travel to the site of an annual Center Directors' meeting may be budgeted in the administrative core. Budgetary constraints, however, preclude expenditures for expensive items of equipment or renovations. Research Career Development and Training Opportunities While formal research training activities cannot be supported directly by this grant mechanism, there is realization that participation in research supported by the RRCMOH program can have a significant impact on the career development of minority faculty members. In addition to the more traditional mechanisms of support for career development (i.e., K04 - research career development award; K15 - individual dentist scientist award; K16 - institutional dentist scientist award; K11 - physician scientist award) the RCMI program of the NCRR is providing funds to cover the cost of faculty development activities for eligible faculty members from minority dental schools or other RCMI eligible institutions. Minority dental school applicants may request up to $100,000 per year for support of faculty development. Funds for faculty development will be provided by the RCMI program of the NCRR through a co- funding arrangement. A single award per center, however, will be made. Candidates for faculty development support through the RCMI program must possess a Ph.D. or other doctoral degree in the health professions, must hold a full-time faculty position at a minority dental school or at an RCMI eligible institution, and be a U.S. citizen or have a permanent immigration visa. Candidates may not hold independent peer reviewed grant support as principal investigators within five years prior to or concurrently with funding of this application. Developmental activities may occur either at a minority dental school, at another institution with appropriate facilities or the developmental experience may be shared between institutions. Candidates will be expected to submit a grant application for extramural research support prior to the completion of the faculty development experience and must remain at the minority dental school or RCMI eligible institution for a period of time equal to the length of faculty development support. Candidates may receive a maximum salary of $30,000 or the current salary received for their academic appointment whichever is less for 50 percent time and effort for the first year. Incremental salary increases of up to $5,000 may be included for the second and third years of the award to a maximum of $40,000. However, salary support may be prorated based on the percent time engaged in faculty developmental activities. The salary request must be commensurate with institutional salary policies for individuals with comparable experience. Because of the necessity for commuting between institutions during the training, up to $3,000 may be requested for travel. Evaluation will be based on the qualifications of the candidate, appropriateness and relevance of expertise to be gained by the candidate, qualifications and suitability of the preceptor, the likelihood that the proposed plan for faculty development will enable the candidate to become an independent investigator capable of successfully competing for independent peer reviewed grant support, and the evidence of institutional commitment to the candidate's further research career development following the faculty development experience. Beyond the RCMI program and the career development grant mechanisms, applicants are encouraged to apply for support for both short and long-term training support through the National Research Service Award (NRSA) program, which can support individual fellowships (F32) institutional training (T32) and short-term training (T35) awards. Another source of support for research training for minority high school, undergraduate or graduate students, post- doctoral fellows and minority faculty at the RRCMOH is obtained through the Supplements For Underrepresented Ethnic Minorities Program. Up to three such supplements may be requested following a Phase II award. For additional information about the minority supplement program contact Dr. Matthew Kinnard at the address listed under INQUIRIES. Research intensive dental school applicants and institutions serving large minority populations are expected to obtain support for training and career development through these mechanisms or other sources since they are not eligible for faculty development support through the NCRR. Applicants may contact Dr. Thomas Valega at the address listed under INQUIRIES, for additional information about career development, training and fellowship opportunities. Scientific and Research Opportunities The following topics are suggested for inclusion in center applications. These, however, are not listed in priority order nor are they exhaustive, and other research topics relevant to minority oral health may be proposed. o Studies of the incidence and prevalence of oral disease in minority populations and subpopulations based on biological factors, physical environment, socioeconomic factors, lifestyle as well as health services delivery factors. o Studies of the relationship of the general health status of minorities to oral health status. o Oral manifestations of AIDS/HIV in minority populations. o Studies of the underlying genetic and environmental factors involved in cleft-lip and palate of native-born and Asian immigrants. o Studies of facial growth patterns in all ethnic minority populations. o Studies of the qualitative and quantitative constituents of bones and teeth (hard tissues) in different ethnic groups. o Studies to establish the relationship between diabetes and periodontitis, particularly juvenile diabetes, refractory periodontitis and early onset periodontitis in minority populations. o Studies of factors contributing to differences in the rates of periodontal diseases in minorities and non- minorities. o Fundamental studies of the molecular events involved in tissue growth and repair, particularly the keloid phenomenon often observed in wound healing of African-Americans. o Etiologic and epidemiologic studies to establish the prevalence of autoimmune disorders such as Sjgren's syndrome, cystic fibrosis and recurrent aphthous stomatitis (RAS) in minority populations. o Follow-up studies to investigate the pathogenesis and treatment of autoimmune disorders that may impact oral health of minorities. o Studies designed to investigate factors contributing to the excess morbidity and mortality associated with oral cancer and precancer in minority populations. o Studies of dietary and nutritional factors in the prevention and intervention of oral diseases in minority populations. STUDY POPULATIONS SPECIAL INSTRUCTIONS TO APPLICANTS REGARDING IMPLEMENTATION OF NIH POLICIES CONCERNING INCLUSION OF WOMEN AND MINORITIES IN CLINICAL RESEARCH STUDY POPULATIONS It is the policy of NIH that applicants for NIH clinical research grants are required to include minorities and women in study populations so that research findings can be of benefit to all persons at risk of the disease, disorder or condition under study. Special emphasis should be placed on the need for inclusion of minorities and women in studies of diseases, disorders and conditions which disproportionately affect them. This policy is intended to also apply to males and females of all ages. If women or minorities are excluded or inadequately represented in clinical research, particularly in proposed population-based studies, a clear compelling rationale should be provided. The composition of the proposed study population must be described in terms of gender/ethnic group. In addition, gender and racial/ethnic issues should be addressed in developing a research design and sample size appropriate for the scientific objectives of the study. This information should be included in form PHS 398 in Items 1-4 of the Research Plan and summarized in Item 5, Human Subjects. Applicants are urged to assess carefully the feasibility of including the broadest possible representation of minority groups. However, NIH recognizes that it may not be feasible or appropriate in all research projects to include representation of the full array of United States racial, ethnic, minority populations. The rationale for studies on single minority population groups should be provided. For the purpose of this policy, clinical research includes human biomedical and behavioral studies of etiology, epidemiology, prevention (and preventive strategies), diagnosis, or treatment of diseases, disorders or conditions, including but not limited to clinical trials. The usual NIH policies concerning research on human subjects also apply. Basic research or clinical studies in which human tissues cannot be identified or linked to individuals are excluded. However, every effort should be made to include tissues from women and racial/ethnic minorities when it is important to apply the results of the study broadly, and this should be addressed by applicants. If the required information is not contained within the application, the application will be returned. Applicants are reminded of the NIH policy, contained on pages 11-13 of the instructions accompanying Form PHS-398 (revised 9/91), concerning documentation of Institutional Review Board (IRB) review and approval of all human studies. According to the policy, all documentation must be submitted either with the application or be received by the Scientific Review Administrator within 60 days after the receipt date of the application. Failure to comply with this policy may result in return of the application. Peer reviewers will address specifically whether the research plan in the application conforms to these policies. If the representation of women or minorities in a study design is inadequate to answer the scientific question(s) addressed and the justification for the selected study population is inadequate, it will be considered a scientific weakness or deficiency in the study design and will be reflected in assigning the priority score to the application. All applications for clinical research submitted to the NIH are required to address these policies. NIH funding components will not award grants or cooperative agreements that do not comply with these policies. LETTER OF INTENT Prospective applicants are asked to submit a letter of intent by March 15, 1994. The letter should contain a descriptive title of the proposed center, the name, address and telephone number of the center director, co-director, identifying information for other key personnel and participating institutions, and the number and title of this RFA. Although a letter of intent is neither required nor binding, and does not enter into the review of subsequent applications, the information that it contains is helpful in planning for the review of applications by allowing NIDR staff to estimate the potential review workload and to avoid possible conflict-of-interest in the composition of the review panel. The letter of intent is to be addressed to Dr. Matthew Kinnard at the address listed under INQUIRIES. APPLICATION PROCEDURES Prospective applicants are advised to communicate with NIDR Extramural Program and Grants Management staff as early as possible in the planning stage of application preparation. NIDR staff are available to assist applicants to ensure that the objectives, structure, and the budget format for the proposed center are acceptable. The research grant application form PHS 398 (rev. 9/91) must be used in applying for these grants. These forms are available at most institutional business offices, from the Office of Grants Inquiries, Division of Research Grants, National Institutes of Health, 5333 Westbard Avenue, Room 449, Bethesda, MD 20892 telephone 301/710-0267 and from the NIDR Extramural Program administrator listed under INQUIRIES. The RFA label available in the form PHS 398 (rev. 9/91) must be affixed to the bottom of the face page of the original application. Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. In addition, the RFA title and number must be typed in item 2a of the face page of the application form and the YES box checked. The instructions accompanying form PHS 398 must be followed as completely as possible, but some modification will be necessary. For example, a new Table of Contents should be prepared giving page numbers for all items in the application. Pagination must be consecutive throughout the application. Each subproject should be identified by number and investigator. Separate detailed budgets for each year for the entire center, core resources, and subprojects and pilot projects should be prepared. A consolidated budget for the center for all years of support should be included (use pages DD-EE, Form PHS 398). Direct and indirect cost estimates must be provided. Funds may be requested for professional, technical, and administrative personnel; core resources; equipment; supplies; consultant services; travel; publication costs; and patient costs directly related to the research. Detailed justification of all budget requests will be required and commitment of collaborating institutions to the center should be fully documented. A summary of financial support from non-NIDR/NCRR sources for studies that will complement and expand the program supported by the NIDR/NCRR must be provided. It should be explained how the support of these studies will further the goals of the center and make it more cost effective. Under Research Plan, the goals of the center should be described and background and significance of the topics being addressed should be discussed. Also, each research project, core, and the faculty development activities should be fully explained in light of how they will contribute to achieving these goals. The organizational and administrative structure, the responsibilities of the director and co-director, individual investigators, and the proposed mechanisms for monitoring scientific progress should be described in detail. Each subproject (regular research project) should be presented as if it were a research grant application (R01) and each pilot project as if it were a small grant (R03) application. Instructions for pages 19-24 of form PHS 398 should be followed. For the Research Plan, a 25-page limitation will apply to each subproject and a 10 page limitation for each pilot project. The length of each core unit description may not exceed 25 pages. A page BB (Abstract form PHS-398) should be completed for the core resources, each subproject, pilot project, and for the entire application. The faculty development component of the application, including the scientific proposal, the formal and informal course of study and the seminars, journal club, and other similar activities should be submitted as an appendix to the application and should not exceed 10 pages. Three sealed letters of reference for each participant must accompany the application. Eligible applicant institutions should contact the RCMI office for specific instructions for preparing the faculty development component of the application. Submit a signed, typewritten original of the application, including the checklist, and three signed, exact photocopies, in one package to: Division of Research Grants National Institutes of Health Westwood Building, Room 240 Bethesda, MD 20892** At the time of submission, two additional copies must also be sent to: H. George Hausch, Ph.D. Extramural Program National Institute of Dental Research 5333 Westbard Avenue, Room 519 Bethesda, MD 20892 Applications must be received by September 21, 1994. If an application is received after that date, it will be returned to the applicant. REVIEW CONSIDERATIONS Upon receipt, applications will be reviewed by NIH staff for completeness and responsiveness. Applications that are incomplete, nonresponsive to this RFA, or exceed the first year budget limit of $500,000 in direct costs will be returned to the applicant without further consideration. However, where indirect costs are assigned to a subcontract and counted as direct costs on the parent grant, the allowable direct cost maximum may be exceeded by the amount of the indirect costs assigned to the subcontract. Costs associated with subcontractual arrangements and/or faculty development activities must be clearly labeled and identified as such within the budget presentation and justification. Applications requesting support of faculty development activities may exceed the budget limit by up to $100,000 in direct cost attributed to faculty development resources provided by the NCRR/RCMI program. Applications that are complete and responsive will be evaluated in accordance with the criteria stated below for scientific and technical merit by a special review committee convened by the NIDR Scientific Review Office. Applications may be subjected to triage by the committee to determine their scientific merit relative to other applications received in response to this RFA. The NIDR will withdraw from further competition those applications judged by triage to be noncompetitive for award and notify the applicant and institutional official. Applications judged to be competitive will undergo further scientific merit review. This review may involve an applicant interview or site visit. The second level of review will be provided by the National Advisory Dental Research Council. Major factors to be considered in the evaluation of applications include: o The scientific merit of all projects proposed, including their significance, originality, feasibility and experimental design. o The technical merit and justification for core resources requested including the extent to which they will assist in developing the center. o The combination of the various pilot and research projects, core units and faculty development activities into a cohesive program which will effectively address the center objectives. o The adequacy of the administrative and organizational structure to ensure efficient inter- and intra-institutional collaboration, interaction and dissemination of information among investigators necessary to attain center objectives. This element is especially important to collaborative efforts of institutions that are geographically separated. In these cases, special care should be taken to provide evidence that the geographical separation will not hinder the collaborative nature of the research projects and also will be cost effective. o The competence and combined efforts of the investigators from collaborating institutions and their commitment to the accomplishment of the research goals and the objectives of the RRCMOH Program. o The qualifications, experience, and commitment of the center director and co-director, including their ability to provide effective leadership of the center and provisions for selection of replacements should it become necessary. o The composition and use of the director's administrative and scientific advisory committees, including an indication of their involvement in the development of the application and procedures for monitoring research progress. o The commitment of collaborating institutions to the center including the adequacy of their facilities, resources and administrative capabilities. o The effectiveness of the faculty development opportunities offered, including the quality of research experiences and mentoring to be provided. o The feasibility of the plan to develop young minority investigators. o The appropriateness of the period of support and budget requested for pilot and research projects, cores, faculty development activities and for the entire center. This includes the distribution of responsibilities and funding among collaborating institutions. o The availability and appropriateness of study populations and the utilization of minorities and women as study subjects. o The potential or proven ability of the center to use NIDR funds to obtain collaborative funding from other sources. The inclusion of projects that are deemed to have little or no scientific merit or that are deemed peripheral to the objectives of the RRCMOH may be considered a reflection of the director's judgement and may adversely affect the overall rating. Component projects without significant and substantial merit will not be recommended for further consideration. Projects with significant and substantial scientific merit but deemed not essential to the success of the center may also be recommended for deletion. AWARD CRITERIA The NIDR appreciates the value of complementary funding from other public and private sources, including foundations and industrial concerns, for activities that will complement and expand those supported by the NIDR and NCRR/RCMI. INQUIRIES Written and telephone inquiries concerning this RFA are encouraged. The opportunity to clarify any issues or questions from potential applicants is welcome. Direct inquiries regarding programmatic issues to: Inquiries regarding career development and NRSA training opportunities may be directed to: Matthew Kinnard, Ph.D. Extramural Program National Institute of Dental Research Westwood Building, Room 509 Bethesda, Maryland 20892 Telephone: (301) 594-7641 FAX: (301) 594-9720 Dr. Thomas Valega Extramural Program National Institute of Dental Research Westwood Building, Room 503 Bethesda, MD 20892 Telephone: (301) 594-6324 Inquiries regarding fiscal matters may be directed to: Ms. Theresa Ringler Extramural Program National Institute of Dental Research Westwood Building, Room 510 Bethesda, MD 20892 Telephone: (301) 594-7629 Inquiries regarding faculty development may be directed to: Dr. Sidney A. McNairy, Jr. Research Centers in Minority Institutions Program National Center for Research Resources Westwood Building, Room 10A10 Bethesda, MD 20899 Telephone: (301) 594-7944 AUTHORITY AND REGULATIONS This program is described in the Catalog of Federal Domestic Assistance No. 93.121. Awards are made under authorization of the Public Health Service Act, Title IV, Part A (Public Law 78-410, as amended by Public Law 99-158, 42 USC 241 and 285) and administered under PHS grants policies and Federal Regulations 42 CFR 52 and 45 CFR Part 74. This program is not subject to the intergovernmental review requirements of Executive order 12372 or Health Systems Agency Review. APPENDIX U.S. Research Intensive Dental Schools or Institutions Receiving More Than $1.0 Million for Research and Training, from the NIDR in Fiscal Year 1991 Institution City State University of Washington Seattle Washington State University of New York at Buffalo Buffalo New York Forsyth Dental Center Boston Massachusetts University of Alabama at Birmingham Birmingham Alabama University of Florida Gainesville Florida University of Pennsylvania Philadelphia Pennsylvania University of Michigan at Ann Arbor Ann Arbor Michigan University of Iowa Iowa City Iowa University of Texas Health Science Center at San Antonio San Antonio Texas University of North Carolina, Chapel Hill Chapel Hill North Carolina University of Rochester Rochester New York University of Minnesota Minneapolis Minnesota University of Southern California Los Angeles California University of California, SF San Francisco California University of Connecticut Health Center Farmington Connecticut Virginia Commonwealth University Richmond Virginia Harvard University Boston Massachusetts American Dental Association Health Foundation Chicago Illinois University of Texas Health Science Center Houston Houston Texas University of California, Los Angeles Los Angeles California Emory University Atlanta Georgia Columbia University New York New York New York Louisiana State University Medical Center New Orleans New Orleans Louisiana Medical College of Georgia Augusta Georgia University of Massachusetts Medical School Worcester Massachusetts Other institutions may be eligible. .
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