Full Text PAR-97-027
 
CENTERS FOR AIDS RESEARCH
 
NIH GUIDE, Volume 26, Number 3, January 31, 1997
 
PA NUMBER:  PAR-97-027
 
P.T. 04

Keywords: 
  0715007 
  Behavioral/Social Studies/Service 
  Clinical Medicine, General 

 
National Cancer Institute
National Heart, Lung and Blood Institute
National Institute of Allergy and Infectious Diseases
National Institute of Child Health and Human Development
National Institute on Drug Abuse
National Institute of Mental Health
 
Application Receipt Date:  June 18
 
PURPOSE
 
Participating Institutes of the National Institutes of Health (NIH)
invite applications for center core grants (P30) to support Centers
for AIDS Research (CFARs).  CFAR cores provide infrastructure and
promote basic, clinical, behavioral and translational AIDS research
activities at institutions that receive significant AIDS funding from
multiple NIH Institutes or Centers.  CFARs foster synergy and improve
coordination of research, support emerging research opportunities,
and promote economy of scale through resources shared by multiple
independent laboratories.  CFARs also encourage other activities that
serve the requirements of AIDS research. CFARs are not intended to be
"Centers of Excellence" in specific areas of AIDS research, but
instead are intended to promote all AIDS research efforts at CFAR
institutions.  Before preparing an application to support a CFAR,
investigators are encouraged to consult with the program staff listed
under INQUIRIES.
 
Definitions
 
Throughout this program announcement (PA) P30 applications to support
CFARs are abbreviated as "CFAR applications" and the corresponding
P30 awards to support CFARs are abbreviated as "CFAR awards."  NIH
CFAR awards support administrative, developmental, basic science and
clinical science cores for AIDS research.  AIDS research and
AIDS-related research are abbreviated as "AIDS research."
 
HEALTHY PEOPLE 2000
 
The Public Health Service (PHS) is committed to achieving the health
promotion and disease prevention objectives of "Healthy People 2000,"
a PHS-led national activity for setting priority areas. This PA,
Centers for AIDS Research, is related to the priority area of HIV
infection.  Potential applicants may obtain a copy of "Healthy People
2000" (Full Report:  Stock No. 017-001-00474-0 or Summary Report:
Stock No. 017-001-00473-1) through the Superintendent of Documents,
Government Printing Office, Washington, DC 20402-9325 (tel
202-512-1800)."
 
ELIGIBILITY REQUIREMENTS
 
Applications may be submitted by domestic for-profit and non-profit
organizations, public and private, such as universities, colleges,
hospitals, laboratories, units of State or Local Government, and
eligible agencies of the Federal Government. Foreign institutions are
not eligible to apply, but CFAR cores may be located at foreign
sites. Racial/ethnic minority individuals, women, and persons with
disabilities are encouraged to apply as principal investigators.
 
o  One CFAR award per Institution.  No institution will receive more
than one CFAR award. Institutions that have significant overlap in
faculty, resources or administration should submit only one
application. Independent campuses that are part of a large multiple
city university are considered to be separate institutions.
 
o  Multi-Institutional CFARs.  Two or more institutions that can
demonstrate a credible plan for collaborative research networks using
CFAR cores may submit an application for a single CFAR award
involving multiple institutions. In particular, investigators at
nearby institutions may prepare a more competitive application as a
multi-institutional CFAR. A multi-institutional CFAR application must
designate a prime institution that will receive the award and provide
details of agreements regarding coordination and support of cores and
activities at other participating institutions.
 
With appropriate justification, CFAR awards may support a core at a
distant site, including a foreign site, that provides a unique
resource such as a primate facility or a high resolution NMR
facility. To achieve administrative efficiency and foster a sense of
community and collaboration, it is expected that each unique resource
would serve as a core for only a single CFAR, and that all cores
within any single institution would be part of the same CFAR award.
 
o  NIH AIDS Funded Research Base.  The purpose of CFARs is to support
the AIDS research activities of investigators at applicant
institution(s) that have significant NIH funding for AIDS research
(NIH AIDS funded research base). The NIH AIDS funded research base is
measured by the total cost of research awards and the number of these
awards to investigators participating in the CFAR. The research base
includes peer-reviewed AIDS grants, cooperative agreements, and
research contracts utilizing only the following mechanisms:  P01,
R01, R03, R21, R29, R35, R37, U01, U10, U19, and K series awards,
R18, and N01 (excluding contracts that primarily fund the production
of materials or services for support of research). Excluded from the
NIH AIDS funded research base are all funds from any source other
than NIH.
 
Multi-institutional CFAR applications may combine the NIH AIDS funded
research of the investigators participating in the proposed CFAR to
meet the funding policies of participating Institutes described
below.
 
o  Funding Policies of Participating Institutes.  CFAR awards are
intended to support AIDS research activities for applicants who
receive significant NIH AIDS funds. Significant NIH AIDS funds are
defined as an NIH AIDS Funded Research Base in excess of $6 million
in annual total cost for the NIH fiscal year  (October 1 to September
30) preceding receipt of CFAR applications.
 
A CFAR award may include funds from multiple NIH Institutes. Usually,
an Institute will contribute to a CFAR award only when that Institute
has provided active AIDS awards totaling more than $1 million in
annual cost to three or more principle investigators who agree to
participate in the CFAR.
 
Generally, the maximum amount of funds from each Institute will be 10
percent of the amount received by the applicant from that Institute
for AIDS research as reported by the Office of AIDS Research for the
NIH fiscal year preceding receipt of CFAR applications.  The actual
amount of funds will be influenced by the potential synergy and
collaboration with Institute-supported investigators demonstrated by
the CFAR application and the percent of Institute-supported AIDS
investigators who agree to participate in the CFAR.
 
A CFAR award (total cost) will be limited to 10 percent of the amount
of funds received by the applicant for AIDS funding as reported by
the Office of AIDS Research for the NIH fiscal year preceding receipt
of the application. Also, no CFAR award will exceed $1.5 million
annually and no participating NIH Institute will provide more than
$1.2 million for any one award
 
o  Applications over $500,000.  NIH Institutes participating in this
CFAR program announcement have agreed to co-fund successful
applicants through a review and award process administered by the
NIAID. Applicants planning to submit a CFAR application requesting
$500,000 or more in direct costs in any year are advised that they
must contact program staff listed under INQUIRIES as they begin to
develop plans. Applicants should contact Dr. Janet Young at the
address listed under INQUIRIES for guidance.  Applications received
without prior staff contact may be delayed in the review process or
returned to the applicant without review (NIH GUIDE, Vol. 22, No. 45,
December 17, 1993).
 
MECHANISM OF SUPPORT
 
The mechanism of support will be the Center Core Grant (P30).
Responsibility for the planning, direction and execution of the
proposed project will be solely that of the applicant.  The total
requested project period may not exceed five years and applicants are
encouraged to apply for five years.  However, applicants are notified
that grants may be awarded for three, four, or five years.
 
RESEARCH OBJECTIVES
 
Background
 
The NIAID CFAR program originated in 1988 and was renewed in 1993.
The mission of the CFAR program and mechanisms for achieving this
mission were developed by the CFAR directors in 1995 and revised in
1996.
 
The mission of the CFARs is to support a multi-disciplinary
environment that promotes basic, clinical, behavioral, and
translational research in the prevention, detection, and treatment of
HIV infection and AIDS. The CFARs accomplish this mission by:
 
- Providing scientific leadership dedicated to AIDS research.
- Providing institutional infrastructure dedicated to AIDS research.
- Stimulating scientific collaboration and translational research.
- Fostering scientific communication.
- Sponsoring training and education.
- Promoting knowledge of CFAR research findings and the importance of
AIDS research  through community outreach.
- Facilitating development of AIDS therapeutics, vaccines and
diagnostics through promotion of scientific interactions between
CFARs and industry.
 
CFARs should promote and encourage activities that enhance
collaboration and coordination of AIDS research and serve the
requirements of all AIDS investigators at the applicant institutions
regardless of funding source.
 
CFAR awards support four different types of cores: administrative,
developmental, basic science, and clinical studies. Each CFAR should
have a single administrative and a single developmental core, and a
number of basic and clinical science cores selected to support
optimally the AIDS research at the applicant institution(s). The
smallest CFAR would consist of one of each type of core. The
definition of what constitutes a basic or clinical core should be
considered sufficiently broad to meet the needs of the applicant
institution(s) and may vary among CFAR applicants. For example,
epidemiology, biostatistics, and behavioral cores could be classified
as either basic or clinical cores.
 
The successful management of AIDS resources with minimal CFAR funding
is an important measure of a CFAR's value to AIDS investigators.
Basic and clinical cores may be supported totally by CFAR funds, only
in part by CFAR funds, or not at all by CFAR funds. Applicants are
encouraged to develop creative collaborations to improve utilization
of existing resources.  Convincing justification will be necessary
for duplication of any basic or clinical core that exists in a
similar form elsewhere in the applicant institution(s). Applicants
should describe how cores with partial or no CFAR funding will be
used to enhance the research of CFAR investigators. For example, a
CFAR core supported by other funding (e.g., an NIAID AIDS Clinical
Trial Unit or a NCI core facility) may become more accessible to AIDS
investigators through CFAR association and coordination.
 
A CFAR has considerable flexibility within its budget to alter
funding of a basic or clinical core, to delete a core, or to initiate
a new core. Policies should be described for changes in CFAR funding
levels of initially proposed cores and for the establishment of new
cores as needed to meet research needs without additional funding.
Applicants should describe how the proposed policies protect and
incorporate the divergent needs of CFAR investigators.
 
An applicant's initial choice of basic and clinical cores is an
important measure of management process. Applicants should describe
the basic and clinical cores to be supported at the time that the
CFAR is awarded, how this choice of cores was selected, other
potential cores that were evaluated but not selected,  mechanisms for
evaluating utilization of proposed cores, and criteria for increased
or decreased funding of these cores during the course of award.
 
Cores should be responsive to the needs of AIDS investigators at
applicant institution(s). Applicants should describe in detail the
operation of the each core (quality control, procedures, safety,
training, etc.). Applicants are encouraged to contact program staff
listed under "Inquiries" to discuss the choice of cores that they are
planning.
 
A CFAR has the responsibility to use its resources in the best manner
to meet the needs of its investigators and the authority to alter
allocation of resources within the guidelines of the CFARs operating
policies and procedures. Applicants should describe how proposed
policies and procedures provide oversight for different types or
levels of decisions and how each of the following individuals or
groups would participate in the decision process: a core director,
the CFAR director, an internal advisory board, CFAR investigators, an
external advisory board, NIH program staff.
 
Additional CFAR supported activities are encouraged. Examples include
industry collaborations, development of minority scientists in AIDS
research, AIDS research communications to non-scientists, addressing
problems in enrollment and retention of women and minority groups in
AIDS clinical trials, international collaborations, and other
activities that meet the AIDS research needs of applicant
institutions.
 
Applicants may wish to contact program staff to discuss the types of
cores and additional activities that they are considering.
 
Commitments for continued funding in the non-competitive continuation
years of all NIH grants are dependent upon the availability of funds.
CFAR awards that receive co-funding from multiple Institutes may
encounter decreased funding if any of these Institutes decreases
their funding commitment. Therefore, applicants should describe
policies and processes for CFAR "down-sizing" decisions should
decreased funding be necessary in continuation years.
 
o  Administrative core.  The administrative core is led by a CFAR
director (P30 grant's principal investigator) who should be a
recognized leader in the field of AIDS research. The administrative
core also may require a senior administrator, a CFAR office that is a
clearly separate entity, and a modest staff for support of CFAR
activities. The responsibilities and time allocation of each staff
person and the proposed operation procedures for the administrative
core should be described in detail.  The administrative core is
responsible for the management of all CFAR activities.
 
The administrative core section of the CFAR application should
present a management plan and strategic plan for the first year of
operation.  Applicants should describe how the CFAR director will
involve other CFAR members in the decision making process for CFAR
activities. These include formation and utilization of internal and
external advisory committees; development of an annual CFAR strategic
plan that includes objective milestones and addresses the missions of
the co-funding Institutes; efficient allocation and utilization of
basic science and clinical core funds; decisions on establishment of
new cores and, if necessary,  decreased CFAR funding of existing
cores; management of developmental funds and decision policies to
meet unforeseen emerging research opportunities; and development of
CFAR-sponsored conferences, seminars and workshops related to the
CFAR mission.
 
The ability to manage the CFAR award will be judged by the clarity
and thoughtfulness of the administrative core section of the
proposal, and evidence for development of a management plan through
acquisition of information, support, and participation of the AIDS
investigators at the applicant institution(s).
 
o  Developmental Core.  The intent of a CFAR developmental core is to
support scientific studies for short periods of time to develop
preliminary data for peer-reviewed research applications. Three
general areas are eligible for support as developmental awards:
investigators new to AIDS research who have not previously received
R01-type awards in AIDS research, feasibility studies, and emerging
research opportunities. Applicants may wish to consult with the
program staff listed under "Inquiries" to discuss how developmental
cores are used at current CFARs.
 
The CFAR administrative core should establish the mechanisms for
allocation of developmental funds and for annual evaluation of
supported activities. CFAR applicants should describe the mechanism
to be used for identification, peer-reviewed selection and outcome
evaluation of projects supported by the developmental core.
Applicants who have current CFARs should describe outcome evaluation
of previously funded developmental projects.
 
The developmental core section should contain a plan for the use of
the first year developmental funds.
 
o  Basic Science Cores.  Basic science cores support shared research
activities that cannot easily be funded through standard research
granting mechanisms. Basic science cores should provide economy of
scale through use by multiple laboratories and foster collaboration
between basic and clinical investigators. Basic science cores should
not substitute for resources that are obtainable commercially or
replace existing resources normally supported by individual research
grants.
 
CFAR applications should describe the mechanisms used to determine
AIDS research basic core needs at the applicant institution(s),
assign priorities to potential cores, and select the basic cores that
are included in the application.
 
CFAR applications should describe the basic science cores to be
supported at the time of  the award and any changes anticipated
during the course of the award. A basic science core should be
designed to support multiple AIDS investigators and applicants should
indicate the anticipated users and the percent time of use by each.
Mechanisms should be described to select users, evaluate annual use,
and justify level of continued CFAR support in comparison with other
AIDS research needs at the applicant institution(s).
 
o  Clinical Cores.  Clinical cores should provide the resources for
AIDS translational research collaboration between clinical and basic
scientists. Activities that will not be supported by a CFAR clinical
core are normal patient care including screening of clinical
specimens, diagnosis, treatment or rehabilitation.  CFAR applications
should describe the mechanisms used to determine AIDS research
clinical core needs at the applicant institution(s), to assign
priorities to potential cores, and to select the clinical cores that
are included in the application.
 
Mechanisms should be described to select users, to evaluate annual
use, and to justify level of continued CFAR support in comparison
with other AIDS research needs at the applicant institution(s).
 
o  Institutional Commitment.  Institutional commitment is
particularly important for the coordination of resources across the
broad areas and potential boundaries of research supported by the
co-funding Institutes. The following are some potential indicators of
institutional commitment to the CFAR:
 
- The position and authority of the CFAR director in the applicant
institution(s) organizational structure: the administrative level in
the institution to whom the CFAR director reports, and the authority
or influence that the CFAR director has with other AIDS projects and
academic departments at the applicant institution(s).
 
- The amount and location of CFAR-specific space allocated to and
controlled by the CFAR director.
 
- The CFAR director's authority in decisions on new faculty or
support personnel.
 
- The applicant institution(s) financial and other resource support
for the CFAR.
 
CFAR BUDGET ITEMS
 
o  Percent Effort.  The percent effort requested should be limited to
time devoted specifically to managing CFAR activities and not to
research activities.  The effort devoted to CFAR activities should
not be that which would normally be supported by research grants.
Information documenting the level of effort on CFAR activities must
be included in the application.  The need for all requested personnel
costs should be thoroughly justified.
 
The percent effort of the CFAR director should be justified with the
director's other responsibilities.  Administrative support (secretary
or an administrative assistant) should be requested for the CFAR
office only for matters directly pertaining to the CFAR.
 
Core directors are CFAR members who are responsible for the overall
technical excellence of a core facility. The CFAR supported percent
effort of core directors involved in research activities should only
include core management time. The CFAR may support technical staff to
provide CFAR services in core facilities.
 
Developmental core funds should only be used for salaries for junior
faculty. Established investigators with R01-type grants are expected
to have salary support from other sources.
 
o  Core Budgets.  Core budgets may include equipment, supplies,
support contracts and other necessary expenses. All items should be
fully justified for allocation of CFAR funds.
 
o  Other Administrative Costs.  This category includes the costs
necessary for the central administration and fiscal management of the
CFAR, including relevant and reasonable costs for reprints, graphics
and publications, for developmental core users.
 
o  Travel.  CFAR directors' meeting(s).  The CFAR directors and one
senior scientist per center will meet two times per year, at the NIH,
at a CFAR site or at the site of a scientific conference that most of
the directors plan to attend. Applicants should include travel funds
specifically for these meetings in the CFAR administration core
budget request. For budget purposes, applicants may assume a total
annual cost for the CFAR directors meeting of $5000.
 
Other Travel Applicants may request and justify travel funds in
addition to the funds required for the two directors' meetings. These
funds should not be used for travel to scientific meetings.  For
example, this travel could promote collaboration among CFAR
investigators and AIDS investigators not in a CFAR program or at
distant cores.  These additional travel funds should not exceed
$5000.
 
INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN
SUBJECTS
 
It is the policy of the NIH that women and members of minority groups
and their subpopulations must be included in all NIH supported
biomedical and behavioral research projects involving human subjects,
unless a clear and compelling rationale and justification is provided
that inclusion is inappropriate with respect to the health of the
subjects or the purpose of the research.  This policy results from
the NIH Revitalization Act of 1993 (Section 492B of Public Law
103-43).
 
All investigators proposing research involving human subjects should
read the "NIH Guidelines for Inclusion of Women and Minorities as
Subjects in Clinical Research," which have been published in the
Federal Register of March 28,1994 (FR 59 14508-14513), and reprinted
in the NIH Guide for Grants and Contract, Volume 23, Number 11, March
18, 1994.
 
APPLICATION PROCEDURES
 
Applicants are strongly encouraged to contact program staff early in
application development with any questions regarding the
responsiveness of their proposal to the goals of this PA.
 
Applications are to be submitted on the grant application form PHS
398 (rev. 5/95) and will be accepted once each year on the receipt
date of June 18.  Application kits are available at most
institutional offices of sponsored research and may be obtained from
the Division of Extramural Outreach and Information Resources,
National Institutes of Health, 6701 Rockledge Drive, MSC 7910,
Bethesda, MD 20892-7910, tel: (301) 710-0267, email:
asknih@odrockm1.od.nih.gov.
 
Page limitations.  The "Research Plan" section of the application
includes the overall description of the CFAR and all cores. The page
limitations have been increased from the normal 25 page limit for a
"Research Plan."  The new page limitation for the "Research Plan" is
50 pages including all tables, graphs, figures, diagrams or charts,
but not including the descriptions of the basic and clinical cores.
An additional 10 pages is allowed for each basic or clinical core.
Applicants are strongly encouraged to be concise.
 
Organization of Application.  The CFAR web site includes suggestions
on how to organize and present information in the CFAR application on
proposed policies and procedures, management plan, strategic plan,
and advisory committee(s) authority and responsibility.  Applicants
are encouraged to follow the application guidelines at the CFAR web
site to facilitate review and award.
 
The label available in the PHS 398 (rev. 5/95) application form must
be affixed to the bottom of the face page of the application.
Failure to use this label could result in delayed processing of the
application such that it may not reach the review committee in time
for review.  In addition, the RFA title and number must be typed on
line 2 of the face page of the application form and the YES box must
be marked.
 
The completed signed original application and three single sided
copies must be sent or delivered to:
 
DIVISION OF RESEARCH GRANTS
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)
 
Two additional single sided copies of the application and all
appendices must be sent or delivered to:
 
Dianne Tingley, Ph.D.
Division of Extramural Activities
National Institute of Allergy and Infectious Diseases
6003 Executive Boulevard MSC 7610
Bethesda, MD  20892-7610
Telephone:  (301) 496-2550
FAX:  (301) 402-2638
Email:  dt15g@nih.gov
 
REVIEW CONSIDERATIONS
 
Upon receipt, applications will be reviewed for completeness by the
NIH Division of Research Grants and for responsiveness to the goals
of this PA by NIAID staff.  Incomplete or non-responsive applications
will be returned to the applicant without further consideration.
Applications that are complete and responsive will be evaluated for
scientific and technical merit by an Initial Review Group (IRG) of
NIAID. As part of the initial merit review, all applications will
receive a written critique, assigned a priority score, and receive a
second level review by an appropriate national advisory council(s) or
board(s).
 
Review Criteria
 
Review criteria are based on the mission of the CFAR Program and
mechanisms for achieving this mission. The initial review group (IRG)
will evaluate CFAR applications for impact, approach, and
feasibility.  In these evaluations, the IRG will also look for
evidence of successful performance from applicants that have had CFAR
awards or similar programs at their institutions.
 
Impact --The effect that a CFAR award would have on an applicant's
AIDS research efforts.
 
1.  The number and percent of all AIDS related research investigators
at applicant institution(s) who agree to participate in the CFAR.
 
2.  The degree of variety in AIDS research projects and disciplines
that commit to participation in and coordination through the CFAR
structure.
 
3.  Institutional commitment, e.g., increased space, institutional
financial support and other institutional resources that will be made
available to AIDS investigators if the CFAR is funded.
 
4.  The choice of cores to support the research base, foster synergy,
coordinate AIDS research collaborations and produce an economy of
scale.
 
5.  The incorporation into the CFAR of resources (cores, projects,
cohorts, trials, etc.) that are supported in part or not at all by
CFAR funds.
 
6.  Targets for scientific communication, outreach, training efforts,
and collaborations with industry.
 
7.  Plans for collaboration between investigators with divergent
disciplines.
 
Approach -- The quality of the CFAR planning and management process.
 
1.  Annual strategic planning process.
2.  Proposed advisory groups and methods for their selection.
3.  Policy and procedures to judge value of cores and reassign
funding priorities.
4.  Policy and procedures of the developmental core.
5.  Policy and procedures to judge the success of developmental core
support.
6.  Policy and procedures to promote translational research
collaborations and technology transfer between basic scientists,
clinical scientists and industry.
7.  Methods for selection of basic and clinical core users and for
prioritization of use.
8.  Proposed AIDS collaboration efforts at the applicant
institution(s).
9.  Plans for scientific communication, outreach, training efforts,
and collaborations with industry
 
Feasibility -- The likelihood that a CFAR will achieve its
objectives.
 
1.  Choice of CFAR director, e.g., managerial experience, commitment,
leadership in AIDS research and at the applicant institution.
2.  Initial choice and quality of proposed cores to support
collaborative studies.
3.  Choice of core directors and key personnel, e.g., qualifications,
competence and commitment.
4.  Authority and responsibility of advisory groups.
5.  Strategic plan for first year of CFAR award.
6.  Evidence of research collaboration between basic and clinical
scientists and indications that a CFAR award will enhance these
collaborations.
7.  Institutional commitment including space, institutional financial
support and other institutional resources and oversight provided for
CFAR activities.
8.  Previous history of support for developmental projects that have
successful outcomes.
9.  Appropriateness of budget of the overall CFAR and of the
individual cores.
 
In addition, applicants must demonstrate adequate provisions for the
protection of human and animal subjects, the safety of the research
environment, and conformance with the NIH "Guidelines for the
Inclusion of Women and Minorities as Subjects in Clinical Research."
 
AWARD CRITERIA
 
Applications will compete for available funds with all other approved
applications. The following will be considered in making funding
decisions:
 
o  quality of the proposed project as determined by peer review
o  availability of funds
o  institute's priority for area of proposed research
 
Conditions of Award
 
The Conditions of Award will incorporate the following items proposed
by the applicant with potential modifications based on
recommendations of the Initial Review Committee:
 
CFAR Policies and Procedures.
CFAR Management Plan.
CFAR Strategic Plan.
CFAR Advisory Committee(s) authority and responsibility.
 
Any changes in these items from the Notice of Award will require
concurrence of NIH.
 
INQUIRIES
 
Inquiries concerning this program announcement are encouraged.  The
opportunity to clarify any issues or questions from potential
applicants is welcome.  Applicants are encouraged to visit the CFAR
web site at http://www.niaid.nih.gov/cfarpa.htm
 
Direct inquiries regarding programmatic issues to:
 
Janet M. Young, Ph.D
Division of AIDS
National Institute of Allergy and Infectious Diseases
Solar Building, Room 2C36B - MSC 7620
Bethesda, MD  20892-7620
Telephone:  (301) 496-6714
FAX:  (301) 402-3211
Email: jy6r@nih.gov
 
Margaret Holmes, Ph.D.
Division of Cancer Treatment, Diagnosis and Centers
National Cancer Institute
6120 Executive Plaza Boulevard, Room 502
Rockville, MD  20852
Telephone:  (301) 496-8531
FAX:  (301) 402-0181
Email:  mh67g@nih.gov
 
Elaine Sloand, Ph.D.
AIDS Coordinator
National Heart, Lung and Blood Institute
Building 31, Room 5A21
Bethesda, MD  20892
Telephone:  (301) 496-3245
FAX:  (301) 354-1290
Email:  es38n@nih.gov
 
Anne Willoughby, Ph.D.
Pediatrics, Adolescent, and Maternal AIDS Branch
National Institute of Child Health and Development
6100 Executive Boulevard, Room 4B11H
Rockville, MD  20852
Telephone:  (301) 496-7339
FAX:  (301) 496-8678
Email:  aw55g@nih.gov
 
Steven W. Gust, Ph.D.
Office on AIDS
National Institute on Drug Abuse
5600 Fishers Lane, Room 10-05
Rockville, MD  20857
Telephone:  (301) 443-6480
FAX:  (301) 443-4100
Email:  sgust@nih.gov
 
Dianne Rausch, Ph.D.
Office on AIDS Research
National Institute of Mental Health
5600 Fishers Lane, Room 10-75
Rockville, MD  20857
Telephone:  (301) 443-7281
FAX:  (301) 443-7274
Email:  dr89b@nih.gov
 
Questions on fiscal issues may be directed to:
 
Ms. Pamela Fleming
Division of Extramural Activities
National Institute of Allergy and Infectious Diseases
Solar Building, Room 4C25 - MSC 7610
Bethesda, MD  20892-7610
Telephone:  (301) 402-6580
FAX:  (301) 480-3780
Email:  pf49e@nih.gov
 
AUTHORITY AND REGULATIONS
 
This program is described in the Catalog of Federal Domestic
Assistance, 93.856 - Microbiology and Infectious Diseases Research
and 93.855 - Immunology, Allergy and Transplantation Research. Awards
are made under authorization of the Public Health Service Act, Title
IV, Part A (Public Law 78-410, as amended by Public Law 99-158, 42
USC 241 and 285) and administered under PHS grant policies and
Federal Regulations 42 CFR Part 52 and 45 CFR Part 74. This program
is not subject to the intergovernmental review requirements of
Executive Order 12372 or Health Systems Agency review.
 
The PHS strongly encourages all grant and contract recipients to
provide a smoke-free workplace and promote the non-use of all tobacco
products.  In addition, Public Law 103-227, the Pro-Children Act of
1994, prohibits smoking in certain facilities (or in some cases, any
portion of a facility) in which regular or routine education,
library, day care, health care or early childhood development
services are provided to children.  This is consistent with the PHS
mission to protect and advance the physical and mental health of the
American people.
 
.

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