INDIVIDUAL PREDOCTORAL NATIONAL RESEARCH SERVICE AWARDS FOR M.D./PH.D. FELLOWSHIPS

Release Date:  April 20, 1999

PA NUMBER: PA-99-089 (This PA has been reissued, see PA-05-151)
                     (Expiration date extended, see NOT-MH-05-011)

Expiration date: August 8, 2005

P.T.

National Institute of Mental Health
National Institute on Drug Abuse
National Institute on Alcohol Abuse and Alcoholism
National Institute of Environmental Health Sciences

THIS PROGRAM ANNOUNCEMENT REPLACES PAR-96-003), WHICH WAS PUBLISHED IN THE NIH
GUIDE, VOL. 24, NO. 37, OCTOBER 20, 1995.

PURPOSE

The National Institute of Mental Health (NIMH), the National Institute on Drug
Abuse (NIDA), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), and
the National Institute of Environmental Health Sciences (NIEHS) provide National
Research Service Awards (NRSAs) to individuals for research training in specified
areas of biomedical and behavioral research.  The purpose of the combined
M.D./Ph.D. fellowships program described in this Program Announcement is to help
ensure that highly trained physician/scientists will be available in adequate
numbers and in the appropriate research areas and fields to meet the Nation"s
mental health, drug abuse and addiction, alcohol abuse and alcoholism and
environmental health sciences research needs.  In addition, this mechanism has
the potential to train clinical investigators who wish to focus their research
endeavors on patient-oriented studies (see http://www.nih.gov/news/crp/97report).

Each Institute has different program goals and initiatives, therefore, potential
applicants should contact the appropriate Institute office, listed under
INQUIRIES, prior to preparing an application, to obtain current information about
each Institute"s program priorities with regard to fellowships.  Information may
also be obtained from the Institute websites listed under INQUIRIES.

HEALTHY PEOPLE 2000

The Public Health Service (PHS) is committed to achieving the health promotion
and disease prevention objectives of "Healthy People 2000," a PHS-led national
activity for setting priority areas. This Program Announcement, Individual
Predoctoral National Research Service Awards for M.D./Ph.D. Fellowships, is
related to the priority areas of human resource development for mental health and
mental disorders, alcoholism, alcohol and other drugs of abuse, tobacco and the
environmental health sciences.  Potential applicants may obtain a copy of
"Healthy People 2000" at http://www.crisny.org/health/us/health7.html

ELIGIBILITY REQUIREMENTS

It is important that prospective applicants consult "National Research Service
Awards Guidelines," published in the NIH GUIDE, Vol. 26, No, 21, June 20, 1997.
It can be found at the following URL:
http://grants.nih.gov/grants/guide/notice-files/not97-009.html

Citizenship: The individual to be trained must be a citizen or a non-citizen
national of the United States or have been lawfully admitted for permanent
residence at the time of award.  A non-citizen national is a person, who,
although not a citizen of the United States, owes permanent allegiance to the
U.S. They are generally persons born in outlying possessions of the United States
(e.g., American Samoa and Swains Island).  Individuals who have been lawfully
admitted for permanent residence must be in possession of a currently valid Alien
Registration Receipt Card (I-551), or must be in possession of other legal
verification of such status.  For example, if an individual is in possession of
the proper validation on his/her passport, a notarized photocopy of the passport
could suffice. Since there is a six-month limitation on this validation, it is
the responsibility of the sponsoring institution to follow-up and assure that the
individual received the I-551 prior to the six month expiration date.

An individual expecting to be admitted as a permanent resident by the earliest
possible award date listed in the fellowship program announcement may submit an
application for an individual NRSA fellowship.  The submission of documentation
concerning permanent residency is not required as part of the initial
application.  Any applicant selected to receive an award must provide a notarized
statement of admission for permanent residence prior to award.

Applicants who have been lawfully admitted for permanent residence, i.e., are in
possession of an Alien Registration Receipt Card or other legal verification of
such status, should check the Permanent Resident box in the citizenship section
on the face page of the fellowship application.  Applicants who have applied for
and have not yet been granted admission as a permanent resident should also check
the same box, but should write in the word "pending."

Individuals on temporary or student visas are not eligible for support from the
NRSA.

Degree Requirements: An applicant for an NIMH, NIDA, NIAAA or NIEHS NRSA
M.D./Ph.D. individual fellowship must have a baccalaureate degree and show
evidence of both high academic performance in the sciences and significant
interest in research in areas of high priority to the participating Institutes. 
The applicant must be enrolled in an M.D./Ph.D. program at an approved medical
school, accepted in a related scientific Ph.D. program, and supervised by a
mentor in that scientific discipline when the application is submitted.  The
typical applicant will apply during the first year of medical school for funding
to begin in the second year, however, applications may be submitted at any stage
of medical school.

Sponsoring Institution: As mentioned above, the applicant must be enrolled in an
M.D./Ph.D. program at an approved medical school and accepted in a related
scientific Ph.D. program.  The institutional setting may be domestic or foreign
(with appropriate justification) private or public (Note: NIEHS will not accept
applications from foreign institutions).  The sponsoring institution must have
staff and facilities available on site to provide a suitable environment for
performing high-quality research training.  The Ph.D. phase of the program may
be conducted outside of the sponsoring institution, e.g., Federal laboratory
including the NIH intramural program.

An NRSA may not be held concurrently with another federally sponsored fellowship
or similar Federal award that provides a stipend or otherwise duplicates
provisions of the NRSA.  An individual may not have more than one competing NRSA
application pending with PHS concurrently, nor be the Principal Investigator on
any other NIH funded grant mechanism.  An NRSA recipient may, however, accept
concurrent educational remuneration from the Department of Veterans Affairs (VA)
and loans from Federal funds.

MECHANISM OF SUPPORT

Awards made under this program announcement will use the INDIVIDUAL PREDOCTORAL
NATIONAL RESEARCH SERVICE AWARDS FOR M.D./PH.D. FELLOWSHIPS (F30) mechanism to
provide combined medical school and predoctoral Ph.D. support for a maximum of
six years, no other predoctoral NRSA support may be received during this time. 
Any exception to these limitations requires a waiver from the Director of the
awarding Institute based on a review of the justification provided by the
individual awardee and his or her sponsor.  Continued support beyond the first
year is dependent upon satisfactory progress toward the combined degree.  Annual
reports are to be provided by the fellow, the Ph.D. department and sponsor, and
the medical school.

Although NRSAs are not usually made for study leading to the M.D., D.O., D.D.S.,
or similar professional degrees, or for study that is part of residency training
leading to a medical specialty, this program is specifically designed to support
training in an established, combined M.D./Ph.D. program.

Allowable Costs

Stipends: The annual stipend for predoctoral individuals will remain fixed for
the period of support, unless the stipend level is changed in the NIH annual
appropriation.  Applicants should consult with Institute Program Staff for the
latest stipend level.  Alternatively, applicants may obtain information about
current stipend levels and other policy documents from the URL for "NIH Training
Related Policy Documents": http://www.nih.gov/training/nrsa.htm

The Tax Reform Act of 1986, Public Law 99-514, describes the tax liability of all
persons supported under the NRSA program.  The stipend is not a payment for
services performed, i.e., it is not a salary.  Further, NRSA fellows are not
considered to be in an employer-employee relationship with the NIH or the
sponsoring institution, and it is unallowable for institutions to seek funds for,
or to charge individual award recipients for, costs normally considered employee
benefits.  The stipend may be supplemented by the sponsoring institution without
obligation to the trainee fellow.  PHS grant funds may not be used for this
purpose.  An institution may also provide additional funds to a fellow in the
form of compensation (as salary and/or tuition remission) for services such as
teaching or serving as a laboratory assistant on a limited part-time basis apart
from the normal training activities.  Under no circumstances may the conditions
of stipend supplementation or the services provided for compensation interfere
with, detract from, or prolong the fellow"s training, nor be for the same
research program.  Refer to the NRSA Guidelines for additional requirements and
information associated with compensation.

Research Allowance: An allowance of up to $2,000 per predoctoral fellow per
twelve month period will be provided to the sponsoring institution to help defray
such expenses as research supplies, equipment, travel to scientific meetings, and
related items for the individual fellows, and to otherwise offset, to the extent
possible, appropriate administrative costs of graduate research training.  The
allowance is provided only upon official activation of the award, and the
sponsoring institution is expected to administer the allowance and disburse the
funds.  If an individual fellow is not in a training status for more than six
months of the award year, only one-half of that year"s allowance may be charged
to the grant.

Tuition and Fees: Tuition and fees will be funded in accordance with the NIH
policy, "Tuition Costs on NIH NRSA Training Grant and Fellowship Awards--New
Policy," NIH Guide, Vol. 25, No. 2, February 2, 1996
(http://grants.nih.gov/grants/guide/notice-files/not96-020.html).
NIH will reimburse 100 percent of the cost of tuition up to $2,000 and 60 percent
of tuition costs above $2,000 for the predoctoral fellow.  Tuition, for the
purposes of this NRSA policy, means the combined cost of tuition, fees, and self-
only health insurance.

RESEARCH OBJECTIVES

Important Note: Applicants must propose to conduct biomedical or behavioral
research in areas of high priority/public health significance to mental health,
drug abuse and addiction, alcohol abuse and alcoholism, or the environmental
health sciences and document that the proposed graduate program and proposed
research project offers them an opportunity to develop expert research skills and
knowledge leading to a research career in these specific areas.  Applications
with marginal or no mental health, drug abuse and addiction, alcohol abuse and
alcoholism, or the environmental health sciences relevance will be considered
unresponsive to this program announcement.  These applications will not be
reviewed and will be returned to the applicant.  This action is not subject to
appeal, therefore, it is of utmost importance that ALL perspective applicants
contact the appropriate Institute office, listed under INQUIRIES, prior to
preparing an application.

The research training experience must provide: a strong foundation in research
design, methods and analytic techniques, the development or enhancement of the
traineesþ ability to conceptualize and think through research problems with
increasing independence, experience in conducting, presenting and publishing
independent research, the opportunity to interact with members of the scientific
community at meetings and workshops (including NIH sponsored meetings), and the
development and documentation of a well thought out career plan to increase the
applicant"s ability to secure federal support for his/her research.  The
applicantþs experience should be under the guidance and supervision of a
committed sponsor who is an active and established investigator in the area of
the applicant"s proposed research.  The research training program should be
carried out in a research intensive environment that includes appropriate human
and technical resources and is demonstrably committed to research training in the
particular program proposed by the applicant so that the applicant can grow as
a creative scientist.

The application must include evidence that instruction in the principles of
responsible conduct of research will be incorporated into the proposed research
training plan. Applications without plans for training in responsible conduct of
research will be considered incomplete and will be returned without review.

The NRSA legislation requires that the Nation"s overall need for biomedical
research personnel be taken into account by giving special consideration to
training physicians who propose to become active biomedical researchers.  The
NIMH, NIDA, NIAAA, and NIEHS recognize the critical importance of training
physicians to become researchers as well as training clinicians to conduct
patient-oriented research.

The enormous complexity of biomedical and behavioral science today prevents the
standard course of study at most medical schools from providing the experience
necessary to develop researchers.  Since scientists who are both medical doctors
and trained investigators play a vital role in helping to bring the highest
scientific standards into basic, clinical, epidemiologic, prevention, and
services research settings, integrated curricula that combine training for the
M.D. degree with extensive research experience have been developed.  There is a
critical need in the mental health, drug abuse and addiction, alcohol abuse and
environmental medicine research arena for physician/scientists with the medical
training to investigate problems of disease in humans.  The graduates of an
M.D./Ph.D. program differ from most other clinicians in having had intensive
research experience in basic science to foster fundamental scientific knowledge
and insight into basic, clinical, epidemiologic, prevention, and services
investigations.  The NIMH, NIDA, NIAAA, and NIEHS expect the fellows trained
under this program to become outstanding scientists interested in research on
mental health and mental illness, drug abuse and addiction, alcohol abuse and
alcoholism, and the environmental health sciences, both as members of
interdisciplinary teams and as individuals able to design, conduct, interpret,
and analyze a sophisticated program of research.

There is a critical need for investigators at the basic/clinical/
epidemiologic/prevention/services interface. New developments (for example, in
neuroscience, especially molecular and cellular neurobiology, neurophysiology,
neuroimaging, neurogenetics, and neural modeling) have made it possible to study
etiological and pathophysiological mechanisms underlying mental disorders, drug
abuse and addiction, and alcohol-related disorders.  Clinical and epidemiologic
research now involves linkage studies to determine the genetic locus of abnormal
genes in a mental disorder, differential hybridization methods to detect possible
abnormalities in genomic regulation, and other basic science methods in
clinically and epidemiologically driven research.

The National Institute of Environmental Health Sciences supports both clinical
and basic mechanistic research into the adverse health effects resulting from
exposure to toxic environmental agents.  It is generally accepted that there
exists a burden of environmentally associated disease or dysfunction on human
health, but the establishment of a cause and effect relationship for particular
environmental exposures to a particular human disease, dysfunction, or decrement
of function has been a consistent challenge.  Although there have been successes,
for example, in aflatoxin induced liver cancer, asbestos exposure, and lead
exposure, the NIEHS seeks to increase its commitment to clinical research to
human studies, and to training the scientists to carry out this research in order
to expand these successes to other areas.  Promising areas in which environmental
exposures are postulated to play a major role in dysfunction or disease include,
but are not limited to, neurodegenerative diseases, endocrine disruption and
reproductive system effects, developmental abnormalities, pulmonary diseases, and
childrenþs health.  There is also great interest in elaboration of the factors
involved in genetic susceptibility, which would explain the variability in the
population in response to exposure to toxicants.  Training opportunities
supported under this announcement are expected to originate in a variety of
disciplines and subspecialties, and responsiveness will mainly be assessed by the
nature of the individual training and research project, and its relevance to a
particular environmental health issue.

Additionally, major changes in research direction and paradigms have led to a
strong public health focus in clinical intervention, health services and
prevention research in NIMH, NIDA, NIAAA and NIEHS.  Because of an acute shortage
of physician/scientists in these critical research areas, potential applicants
who are interested in such careers are especially encouraged to apply.  A wide
range of disciplines are appropriate for Ph.D.s, including (but not limited to)
public health, epidemiology, economics, bioethics, computer science and
pharmacy).  Applicants are strongly advised to consult with NIH staff.

Racial/ethnic minority individuals, women, and persons with disabilities are
encouraged to apply.

SPECIAL REQUIREMENTS

Awards must be activated within six months of receipt of award notice (see below
for application receipt, review, and start dates).  No funds may be disbursed
until the individual has started training under the award and an Activation
Notice (PHS 416-5) has been submitted to and accepted by the NIH awarding
component.

Individuals are required to pursue their M.D./Ph.D. training program on a full-
time basis, devoting at least 40 hours per week to the training program.

INCLUSION OF WOMEN AND MINORITIES IN RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of the NIH that women and members of minority groups and their
subpopulations must be included in all NIH supported biomedical and behavioral
research projects involving human subjects, unless a clear and compelling
rationale and justification is provided that inclusion is inappropriate with
respect to the health of the subjects or the purpose of the research.  This
policy results from the NIH Revitalization Act of 1993 (Section 492B of Public
Law 103 43).

All investigators proposing research involving human subjects should read the
"NIH Guidelines for Inclusion of Women and Minorities as Subjects in Clinical
Research," which was published in the Federal Register of March 28, 1994 (FR 59
14508-14513) and in the NIH Guide for Grants and Contracts, Vol. 23, No. 11,
March 18, 1994, available on the web at:
http://grants.nih.gov/grants/guide/notice-files/not94-100.html

INCLUSION OF CHILDREN AS PARTICIPANTS IN RESEARCH INVOLVING HUMAN SUBJECTS

It is the policy of NIH that children (i.e., individuals under the age of 21)
must be included in all human subjects research, conducted or supported by the
NIH, unless there are scientific and ethical reasons not to include them.  This
policy applies to all initial (Type 1) applications submitted for receipt dates
after October 1, 1998.

All investigators proposing research involving human subjects should read the
"NIH Policy and Guidelines on the Inclusion of Children as Participants in
Research Involving Human Subjects" that was published in the NIH Guide for Grants
and Contracts, March 6, 1998, and is available at the following URL address:
http://www.nih.gov/grants/guide/notice-files/not98-024.html

Investigators also may obtain copies of the policy from the program staff listed
under INQUIRIES. Program staff may also provide additional relevant information
concerning the policy.

APPLICATION PROCEDURES

Prospective applicants should contact the relevant Institute Program Staff listed
under INQUIRIES, for pre-application consultation and information regarding the
application process.  The Individual National Research Service Award application
kit PHS 416-1 (rev. 8/95) must be used in applying for fellowships. These forms
are available at most institutional offices of sponsored research and may be
obtained from the Division of Extramural Outreach and Information Resources,
National Institutes of Health, 6701 Rockledge Drive, MSC 7910, Bethesda, MD
20892-7910, Telephone: (301) 435-0714, FAX: (301) 480-0525, Email:
GrantsInfo@nih.gov.  Application kits are also available on the Internet at:
http://www.nih.gov/grants/forms.htm

The number and title of this program announcement must be typed in Item 3 on the
face page of the application form.  At least three completed letters of reference
in sealed envelopes must be attached to the application.  Applications without
the required number of reference letters will be returned without review.

Application Receipt and Review Schedule:

Applications for the NIMH, NIDA, NIAAA or NIEHS M.D./Ph.D. predoctoral fellowship
will be accepted and reviewed three times a year according to the following
schedule:

Application Receipt Date:      Apr 5      Aug 5     Dec 5
Review Meeting:                Jun/Jul    Oct/Nov   Feb/Mar
Notification:                  Aug/Sep    Dec/Jan   Apr/May
Earliest Possible Start Date:  Sep        Jan       May

Applications received after these receipt dates are subject to assignment to the
next cycle, or may be returned to the applicant upon request by the applicant.

An original and two copies of the completed and signed application are to be
submitted to:

CENTER FOR SCIENTIFIC REVIEW
NATIONAL INSTITUTES OF HEALTH
6701 ROCKLEDGE DRIVE, ROOM 1040 - MSC 7710
BETHESDA, MD  20892-7710
BETHESDA, MD  20817 (for express/courier service)

Applicants are advised to pay special attention to the following important items
in PHS 416-1:

Part I (Prepared by Applicant):

Item 5. Training Under Proposed Award. Identify the Ph.D. discipline according
to the NIH Lexicon of NRSA disciplines on page 27 of the instructions. 
Candidates who expect to receive a Ph.D. in Neuroscience should enter a code
number of 188 (Neurobiology).

Item 22. Scholastic Performance.  In addition to the information requested in the
application, applicants should provide scores for MCAT, GRE, and other exams
relevant to medical and graduate school that they have taken recently.

Item 29a. Activities Under Award.  Typically, an M.D./Ph.D. student spends the
first 2 years of the program in medical school courses with a limited amount of
time devoted to Ph.D. work, the third and fourth years of support are spent on
Ph.D. work, and the last 2 years are used to complete medical school. Applicants
should describe how they expect to divide their time between medical and graduate
school, e.g., medical school courses, graduate school courses, research, research
training, etc., during both the school year and the summer for each year of the
program.  A minimum of 40 hours/week are required for support under the NRSA
program.

Item 29b. Research Proposal.  All applicants should provide a research plan,
including a description of a research proposal in which they will be involved as
part of their training.  The plan should include substantive detail that adds to
the information about time allocations requested in Item 29a.

Part II (Prepared by Sponsor):

Items 32 and 33. Sponsor"s Previous Fellows/Trainees, Training Plan, Environment,
and Research Facilities.  The sponsor must currently be funded to conduct
independent research (e.g., Principal Investigator on an R01 or equivalent) and
must describe past experience in the guidance of other research trainees and
fellows.  In addition, the sponsor must describe in detail his/her commitment to
and proposed role in guiding the individual applicant.  The chairman of the
graduate committee for the Ph.D. program must also describe the department"s
commitment to and proposed role in guiding the
individual applicant and any modifications to the department"s usual Ph.D.
requirements that are necessary to facilitate this trainee"s special needs.

The application must include evidence that training in the principles of
responsible conduct of research will be incorporated in the research experience
of each fellow.  This should be presented under Item 33.  Issues such as conflict
of interest, data recording and retention, professional standards and codes of
conduct, responsible authorship, and ethics in biological and behavioral research
can provide the substantive base of such training.

REVIEW CONSIDERATIONS

Applications will be assigned on the basis of established PHS referral
guidelines.  Applications that are complete will be evaluated for scientific and
technical merit by an appropriate peer review group convened in accordance with
the standard NIH peer review procedures.  As part of the merit review, all
applications will receive a written critique and will be assigned a priority
score.

Review Criteria

The F30 individual M.D./Ph.D. predoctoral fellowship is designed to train future
generations of outstanding clinician/scientists committed to pursuing a career
in mental health, drug abuse, alcohol abuse and alcoholism, or environmental
health sciences research.  The review of an application will focus on the
following: the applicant, the research training plan, the sponsor, and the
institutional environment/commitment.  Information from the letters of reference
will be used to inform considerations of these factors, and the final priority
score will reflect the overall evaluation of the entire application.

Applicant:

o  the applicant"s potential for, and commitment to, a productive scientific
career.  The reviewers may take into account the applicant"s history as a
student, as well as past and current involvement in research activities.

Research Training Plan:

o  objectives, design, and direction of the proposed research program,

o  specificity and clarity of the description of the research skills and
knowledge to be acquired and objective evaluation of progress in each area,

o  overall coherence and potential of the research training plan to provide the
fellow with individualized supervised experiences that will develop research
skills,

o  clarity, completeness, originality, and significance of the goals of the
proposed research training plans,

o  adequacy of knowledge of relevant literature and current methods in the
proposed research area,

o  Potential of proposed research training to serve as a sound foundation that
will lead the applicant to a productive career in mental health, drug abuse and
addiction, alcohol abuse and alcoholism, or the environmental health sciences
research,

o  adequacy of plans for the protection of human subjects, animals, or the
environment, to the extent they may be adversely affected by the research
proposed,

o  adequacy of plans to include women, children and minorities as subjects in
research, if applicable,

o  adequacy of plans to provide training in the responsible scientific conduct
of research.

Sponsor:

o  caliber of the sponsor as a researcher, including successful competition for
research support,

o  evidence of the proposed sponsor"s understanding of and commitment to
fulfilling the role of sponsor and mentor,

o  evidence of an understanding of the applicant"s research training needs and
a demonstrated ability, on the part of the sponsor, to assist in meeting those
needs,

o  past research training record of the sponsor in terms of the rate at which
former predoctoral trainees obtain their doctoral degree and go on to
postdoctoral or other scientific careers.

Institutional Environment/Commitment:

o  training environment including the institutional commitment to research
training and career development,  the quality of the facilities and related
resources (e.g., equipment, laboratory space, computer time, subject populations)
and the availability of research support.

AWARD CRITERIA

The responsibility for award decisions resides solely with authorized program
staff of the Institutes. The following criteria will be used in making award
decisions: (1) overall merit of the application, (2) relevance of the application
to the research priorities and mission of the awarding institute and program
balance, and (3) availability of funds.

INQUIRIES

Inquiries are encouraged.  Prospective applicants are encouraged to visit each
Institute"s Internet Website in order to obtain current information about program
priorities, research topics of interest, and policy guidelines:

NIMH: http://www.nimh.nih.gov/grants/rtcd.htm
NIDA: http://www.nida.nih.gov/ResTrainingSites.html
NIAAA: http://silk.nih.gov/silk/niaaa1/grants/grants.htm
NIEHS: http://www.niehs.nih.gov/dert/resprogs.htm

Inquiries regarding programmatic issues may be directed to:

Henry Khachaturian, Ph.D.
Office of Science Policy and Program Planning
National Institute of Mental Health
6001 Executive Boulevard, Room 8208, MSC 9667
Bethesda, MD  20892
Telephone: (301) 443-4335
FAX: (301) 443-3225
Email: hkhachat@mail.nih.gov

Andrea Baruchin, Ph.D.
Science Policy Branch
National Institute on Drug Abuse
6001 Executive Boulevard, Room 5230, MSC 9591
Bethesda, MD  20892
Telephone:  (301) 443-6071
FAX:  (301) 443-6277
Email:  ab47j@nih.gov

Tina Vanderveen, Ph.D.
Division of Basic Research
National Institute on Alcohol Abuse and Alcoholism
6000 Executive Boulevard, Room 402, MSC 7003
Bethesda, MD  20892
Telephone:  (301) 443-2531
FAX:  (301) 594-0673
Email:  tvanderv@willco.niaaa.nih.gov

Carol Shreffler, Ph.D.
Organ Systems and Toxicology Branch  EC-23
National Institute of Environmental Health Sciences
P.O. Box 12233
Research Triangle Park, NC  27709
Telephone: (919) 541-1445
FAX: (919) 541-5064
Email: shreffl1@niehs.nih.gov

Direct inquiries regarding fiscal matters to:

Diana S. Trunnell
Grants Management Branch
National Institute of Mental Health
6001 Executive Boulevard, Room 6115, MSC 9605
Bethesda, MD  20892-9605
Telephone:  (301) 443-2805
FAX:  (301) 443-6885
Email:  dtrunnel@mail.nih.gov

Gary Fleming
Grants Management Branch
National Institute on Drug Abuse
6001 Executive Boulevard, Room 3131, MSC 9541
Bethesda, MD  20892
Telephone:  (301) 443-6710
FAX:  (301) 443-9127
Email:  gf6s@nih.gov

Judy Simons
Grants Management Branch
National Institute on Alcohol Abuse and Alcoholism
6000 Executive Boulevard, Suite 504, MSC 7003
Bethesda, MD  20892-7003
Telephone:  (301) 443-2434
FAX:  (301) 443-3891
Email:  js182a@nih.gov

Jackie Russell
Grants Management Branch  EC-22
National Institute of Environmental Health Sciences
P.O. Box 12233
Research Triangle Park, NC  27709
Telephone:  (919) 541-0751
FAX:  (919) 541-2860
Email:  russell@niehs.nih.gov

AUTHORITY AND REGULATIONS

This program is described in the Catalog of Federal Domestic Assistance Nos.
93.272, 93.278, 93.282, and 93.894.  Awards are made under authorization of the
Public Health Service Act, Title IV, Part A (Public Law 78-410, as amended by
Public Law 99-158, 42 USC 241 and 285) and administered under NIH grants policies
and Federal Regulations 42 CFR 66 and 45 CFR Part 74.  This program is not
subject to the intergovernmental review requirements of Executive Order 12372 or
Health Systems Agency review.  Awards will be administered under NIH policy as
stated in the NIH Grants Policy Statement (October 1, 1998).

NIH strongly encourages all grant and contract recipients to provide a smoke-free
workplace and promote the nonuse of all tobacco products.  In addition, Public
Law 103-227, the Pro-Children Act of 1994, prohibits smoking in certain
facilities (or in some cases, any portion of a facility) in which regular or
routine education, library, day care, health care or early childhood development
services are provided to children.  This is consistent with the PHS mission to
protect and advance the physical and mental health of the American people.



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