NICHD TRANSGENIC MOUSE DEVELOPMENT FACILITY NIH GUIDE, Volume 24, Number 39, November 3, 1995 P.T. 34 Keywords: 0780035 National Institute of Child Health and Human Development The National Institute of Child Health and Human Development (NICHD) Transgenic Mouse Development Facility (NTMDF) is a research resource that develops transgenic mice for investigators requiring these services. It was established to provide reliable and affordable transgenic mice in a timely manner primarily to biomedical research grantees supported by the National Institutes of Health. Specifically, the NTMDF supports basic biomedical research by providing investigators with the following customized services: o Analyzing DNA constructs for microinjection. o Microinjecting DNA constructs into fertilized one-cell mouse eggs and reimplanting them into pseudopregnant recipient females. o Testing potential founders for DNA integration. o Producing at least two transgenic (integration-positive) mice. o Fast turnaround time (10-12 weeks) Information and applications for services should be requested from the Director, NTMDF. Completed applications may be submitted anytime to the NTMDF Director for review. Review is completed within two weeks of receipt. All applications are handled confidentially and those DNA constructs approved are microinjected at the NTMDF. The Investigator is charged a non-refundable fee of $500 per construct for initial analysis. An additional fee of $2000 per construct is assessed if two or more transgenic mice are produced. The NTMDF is supported by a contract award from the National Institute of Child Health and Human Development, NIH. INQUIRIES Direct requests for information and applications regarding this research resource to: Carl A. Pinkert, Ph.D., Director NICHD Transgenic Mouse Development Facility c/o The University of Alabama at Birmingham 1670 University Boulevard, VH-227 Birmingham, AL 35294-0019 Telephone: (205) 934-2998 Email: Pinkert@cmed.bhs.uab.edu Direct programmatic inquiries to: Allan Lock, D.V.M. NTMDF Project Officer National Institute of Child Health and Human Development Building 6100, Room 4B01, MSC-7510 Bethesda, MD 20892-7510 Telephone: (301) 496-5541 Email: LockA@HD01.NICHD.NIH.GOV .
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