Notice Number: NOT- HL-08-110

Key Dates
Release Date: January 25, 2008

Issued by
National Heart, Lung, and Blood Institute (NHLBI), (http://www.nhlbi.nih.gov/)

The purpose of this notice is to announce that the NHLBI will now accept applications that propose to work with all vertebrate species to elucidate the natural molecular and cellular adaptations to extreme environmental conditions that would rapidly evoke life-threatening cardiovascular or respiratory responses in humans.  Previously, applications were restricted to studies of evolved adaptations in mammalian species. The scope is now broadened to support studies of all vertebrate species evolved to thrive under extreme environmental conditions including food scarcity, limited access to oxygen, temperature extremes, high salinity, or similarly harsh habitats.  The overall objective remains the same: to identify new targets for development of novel therapeutic interventions to treat and prevent heart, blood, and lung diseases and sleep disorders in humans.

A description of other requirements for this funding opportunity may be found at: http://grants.nih.gov/grants/guide/pa-files/PAR-07-102.html

We encourage your inquiries concerning this funding opportunity and welcome the opportunity to answer questions from potential applicants.

Inquiries

Scientific/Research Contacts:

David Lathrop, Ph.D.
Division of Cardiovascular Diseases, NHLBI
National Institutes of Health
6701 Rockledge Drive
Room 8174, MSC 7956
Bethesda, MD 20892-7934
Telephone: (301) 435-0504
FAX: (301) 480-1335
Email: LathropD@nhlbi.nih.gov

Financial or Grants Management Contacts:

David Reiter
Office of Grants Management
Division of Extramural Research Activities, NHLBI
National Institutes of Health
Rockledge II, Room 7172
6701 Rockledge Drive
Bethesda, MD 20892
Telephone: (301) 435-0170
FAX: (301) 480-3310
Email: reiterd@nhlbi.nih.gov