Notice Number: NOT-ES-09-007
Release Date: July, 23 2009
National Institute of Environmental Health Sciences (http://www.niehs.nih.gov)
National Cancer Institute (http://www.cancer.gov)
The National Institute of Environmental Health Science (NIEHS) and the National Cancer Institute (NCI) intend to promote a new initiative by publishing a set of Requests for Applications (RFA) to solicit applications for research on the Breast Cancer and the Environment Research Program (BCERP). These activities will support parallel ongoing epidemiological investigations and new laboratory and epidemiological studies on environmental influences on breast cancer risk. The BCERP is among a select few NIH projects supporting transdisciplinary research on the interaction of environmental factors, including chemical, physical, biological, and social environmental, with genetic factors within windows of susceptibility throughout a woman’s lifespan.
This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.
These FOAs are expected to be published in September 2009 with an expected receipt date of November 30, 2009.
These FOAs will utilize the U01 mechanism. Details of the planned funding opportunity announcements (FOAs) are provided below.
Research Initiative Details
This Notice encourages investigators with expertise and insights into this area of the role of environmental exposures on the development of the mammary gland and breast cancer risk to begin to consider applying for these new FOAs. In addition, collaborative investigations combining expertise in epidemiology, laboratory-based investigation, and community outreach and translation will be encouraged and these investigators should also begin considering applying for this application.
Among the areas of research encouraged in this initiative are research examining the mechanisms that underlie the effects of environmental exposure on female development, reproductive health, and breast cancer risk across the lifespan, as well as research designed to improve the translation of existing knowledge of the effects of common exposures and psychosocial stress into strategies for the prevention and treatment of breast cancer. Thus, the research supported by the FOAs will consist of multi-disciplinary research teams drawn from networks or other collaborative groups to conduct high-quality, transdisciplinary research in the environmental health aspects of breast cancer.
The FOAs to be issued invite applications from eligible institutions to participate in:
The BCERP has been groundbreaking in its transdisciplinary approaches; that is, a methodology and practice that utilizes multiple forms of expertise, including community members and activists in an integrated fashion so as to generate new hypotheses and tools. The program optimized involvement of community members and advocates in the research process to consider the etiology of environmental impact on breast cancer at the genetic, metabolic, cellular, individual, and environmental, at the physical, as well as social levels. The next phase of the program is intended to complete the initial population study, to expand upon the recent findings of the BCERP in identifying biomarkers of common exposures, links to genetic polymorphisms, chemical agent-induced changes on mammary gland architecture and cellular phenotypes, and to continue efforts to include and inform the engaged breast cancer community. In addition, efforts will be made to stimulate basic and applied research to exploit the latest concepts in breast cancer pathogenesis and environmental health.
APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.
Interested parties may contact:
Leslie Reinlib, PhD
Division of Extramural Research & Training
National Institute of Environmental Health Sciences
530 Davis Drive; Room 3072
Research Triangle Park, NC 27713 (for regular/express/courier delivery)
Telephone: (919) 541-4998
Fax: (919) 316-4606
Gary L. Ellison, PhD, MPH
Division of Cancer Control and Population Sciences
National Cancer Institute
6130 Executive Boulevard, EPN Room 5108, MSC 7324
Bethesda, MD 20892-7324 (for U.S. Postal Service express or regular mail)
Rockville, MD 20852 (for express/courier delivery)
Telephone: (301) 402-1853
Fax: (301) 402-4279
Weekly TOC for this Announcement
NIH Funding Opportunities and Notices
Office of Extramural
National Institutes of Health (NIH)
9000 Rockville Pike
Bethesda, Maryland 20892
Department of Health
and Human Services (HHS)