NIEHS POLICY FOR APPLICANTS PLANNING TO SUBMIT R21 FOR PA-02-093 RELEASE DATE: January 29, 2004 NOTICE: NOT-ES-04-004 National Institute of Environmental Health Sciences (NIEHS) (http://www.niehs.nih.gov) The purpose of this notice is to alert the scientific community that effective immediately, applicants requesting R21 support through the Program Announcement PA-02-093, Environmentally Induced Cardiovascular Malformations, by the NIEHS will comply with the requirements of the current NIH-wide Program Announcement PA-03-107, Exploratory/Developmental Research Grant Award , available at http://grants.nih.gov/grants/guide/pa-files/PA-03-107.html. Specifically, the NIEHS will accept R21 applications that request a project period of up to two years with a combined budget for direct costs of up to $275,000 for a two-year period. For PA-02-093, this is an increase from $100,000 per year for a two-year period. The request should be tailored to the needs of the project, but no more than $200,000 may be requested in any single year, and the research plan may not exceed 15 pages. Direct your questions about this notice to: J. Patrick Mastin, Ph.D. Chief, Cellular, Organ and Systems Pathobiology Branch Division of Extramural Research and Training National Institute of Environmental Health Sciences P.O. Box 12233, MD EC-23 Research Triangle Park, NC 27709 Phone: 919-541-3289 Fax: 919-541-5064 Email: mastin@niehs.nih.gov

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