Notice of NIDDK’s Intent to Support a GWAS Study through CIDR

Notice Number: NOT-DK-07-004

Key Dates
Release Date:  February 7, 2007

Issued by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (http://www.niddk.nih.gov)

National Institute of Diabetes & Digestive & Kidney Diseases announces that it will set aside $1.5 M for support of applications to the Center for Inherited Disease Research (CIDR) for SNP genome wide association studies (GWAS) of type 2 diabetes in US populations that have the increased burden of the disease.  These populations include African-Americans, Hispanic/Latino Americans, American Indians, Alaska Natives, Asian-Americans, Native Hawaiians and other Pacific Islanders. More information on the prevalence of diabetes in the US can be found at http://diabetes.niddk.nih.gov/dm/pubs/statistics/index.htm#10.

GWAS studies for type 2 diabetes have been conducted in populations from Finland, United Kingdom, and Sweden but have not been conducted in the populations most afflicted with diabetes.  In order to identify genetic contributions to the health disparities observed in type 2 diabetes, similar studies are needed in populations with the highest burden of disease.  These may be either US populations or founder populations of these ethnic groups.  If a non-US population is proposed, its relevance to the US population needs to be justified.

CIDR is a genotyping facility funded by NHGRI with contributions from 13 NIH Institutes. Applicants need to have active NIH grant studying diabetes in one of these populations. The samples need to have been collected and subjects phenotyped prior to the application. Applications to CIDR will be accepted for the March 1 deadline.  More information on submission to CIDR can be found on the Website: http://www.cidr.jhmi.edu/.

NIH is currently considering a new data sharing policy for Whole Genome Association Studies.  A draft policy can be found athttp://grants.nih.gov/grants/guide/notice-files/not-od-06-094.html NIDDK anticipates that a similar sharing policy will apply to this and all other WGA studies.

Inquiries

For questions regarding this specific NIDDK notice please contact:

Catherine McKeon, Ph.D.
Senior Advisor for Genetic Research, NIDDK
6707 Democracy Blvd #6103
National Institute of Diabetes & Digestive & Kidney Diseases
National Institutes of Health
Bethesda MD 20892
Phone: (301) 594-8810
FAX:  (301) 480-3503
Email: cm67w@nih.gov

For questions regarding the CIDR application process please contact:

Jerry Roberts, Ph.D.
Scientific Review Administrator and Executive Director, CIDR Board of Governors
Center for Inherited Disease Research (CIDR)
Suite 4076 MSC 9306
5635 Fishers Lane
National Human Genome Research Institute
National Institutes of Health
Bethesda, MD 20892-9306
(courier: use Rockville, MD 20852)
Phone: (301) 402-8837
Fax: (301) 435-1580
E-mail: jr39m@nih.gov

 


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