Notice of Availability of Nicotine Research Cigarettes through NIDA's Drug Supply Program

Notice Number: NOT-DA-14-004

Key Dates
Release Date: January 24, 2014

Related Announcements
RFA-OD-13-013
RFA-OD-13-014
RFA-OD-13-015
RFA-OD-13-016
RFA-OD-13-011
RFA-OD-13-010
RFA-OD-13-012

Issued by
National Institute on Drug Abuse (NIDA)

Purpose

This Notice replaces NOT-DA-13-002 to update the catalog of research cigarettes and ordering guidelines from the NIDA Drug Supply Program.

This Notice communicates the availability and procedures for acquisition of nicotine research cigarettes (NRC) through the NIDA Drug Supply Program (DSP).  Information provided in this Notice will help the NIDA DSP and research investigators interested in tobacco research effectively plan for the use of NRCs and for responses to Funding Opportunity Announcements.

Limited quantities of NRCs manufactured under the NIDA DSP are available to research investigators under specified parameters such as nicotine and tar yields ,and type as reduced nicotine (RN), reduced nicotine and menthol (RN-Men), reduced nicotine and high tar (RN-HT),  reduced nicotine, high tar and menthol (RN-HT-Men), and conventional nicotine (CN). The NIDA DSP will consider requests for its current inventory of NRCs from researcher investigators funded through the NIH to conduct tobacco science research. 

To facilitate planning for either usage of the current inventory of NRCs, or future manufacturing needs, the NIDA DSP requests that research investigators who intend to submit requests for NRCs from the NIDA DSP send an email request with the following information: 1) anticipated total quantity (carton) of each type of NRC needed with their Tobacco Product Master File (TPMF) codes and Type, 2) the requested timeline and amounts for initial receipt, and 3) requested timeline of replenishment of each type of NRC.  For those research investigators who have NIDA/NIH grants, they can submit their request according to the NIDA DSP Guidelines for Research Chemicals, Controlled Substances, and Nicotine Research Cigarettes (NRC). For more information, please email NIDANRCSupply@mail.nih.gov

Characteristics of the NRC inventory are described in the following table:

TPMF Code

Type

Specifications
Nicotine Yield

Specifications
Tar Yield

NRC 100

RN-HV

0.02 ± 0.01

3 ± 1.5

NRC 101

RN-HV-Men

0.02 ± 0.01

3 ± 1.5

NRC 102

RN

0.03 ± 0.01

9 ± 1.5

NRC 103

RN-Men

0.03 ± 0.01

9 ± 1.5

NRC 104

RN-Men

0.04 ± 0.02

13 ± 2

NRC 105

RN-HT-Men

0.04 ± 0.02

13 ± 2

NRC 200

RN

0.07 ± 0.02

9 ± 1.5

NRC 201

RN-Men

0.07 ± 0.02

9 ± 1.5

NRC 300

RN

0.12 ± 0.03

9 ± 1.5

NRC 301

RN-Men

0.12 ± 0.03

9 ± 1.5

NRC 302

RN-HT-Men

0.16 ± 0.03

13 ± 2

NRC 400

RN

0.26 ± 0.06

9 ± 1.5

NRC 401

RN-Men

0.26 ± 0.06

9 ± 1.5

NRC 402

RN-HT

0.33 ± 0.06

13 ± 2

NRC 405

RN-HT-Men

0.4 ± 0.08

13 ± 2

NRC 404

RN-HT

0.6 ± 0.12

13 ± 2

NRC 500

RN-HT

0.7 ± 0.15

13 ± 2

NRC 501

RN-Men

0.6 ± 0.12

9 ± 1.5

NRC 600

CN

0.8 ± 0.15

10.5 ± 1.5

NRC 601

CN-Men

0.8 ± 0.15

10.5 ± 1.5

NRC 602

CN-HT-Men

1.1 ± 0.2

16 ± 2

NRC 700

LTNR-HT

1.6 ± 0.3

16 ± 2

NRC 701

LTNR-Men

1.2 ± 0.2

12 ± 2

 

*Legend:

     

RN-HV

Reduced Nicotine-High Ventilation

RN-HV-Men

Reduced Nicotine-High Ventilation Menthol

RN

Reduced Nicotine

RN-Men

Reduced Nicotine-Menthol

RN-HT

Reduced Nicotine-High Tar

RN-HT-Men

Reduced Nicotine-High Tar-Menthol

CN

Conventional Nicotine

CN-Men

Conventional Nicotine-Menthol

CN-HT-Men

Conventional Nicotine-High Tar-Menthol

LTNR-HT

Low Tar/Nicotine Ratio-High Tar

LTNR-Men

Low Tar/Nicotine Ratio-Menthol


Inquiries

Please direct all inquiries to:

Hari H. Singh, PhD/ Phylicia Porter, MPH
National Institute on Drug Abuse (NIDA)
Telephone: 301-435-1310/ 301-435-1692
Email: NIDANRCSupply@mail.nih.gov

 


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