PEDIATRIC PRECLINICAL TESTING PROGRAM RELEASE DATE: August 14, 2003 NOTICE: NOT-CA-03-036 National Cancer Institute (NCI) (http://www.nci.nih.gov) The Cancer Therapy Evaluation Program (CTEP), Division of Cancer Treatment and Diagnosis (DCTD) of the National Cancer Institute (NCI) is seeking support to systematically test agents in childhood cancer pre-clinical models. The primary objective of this RFP is to identify and calibrate a panel of predictive pediatric pre-clinical models to inform pediatric oncologists' prioritization of new agents for evaluation in children with cancer. The Contractor will systematically test 10-15 agents or combinations of agents per year against a panel of pre-clinical models of the childhood cancers that occur most commonly in children. The intended outcome of the project is to improve survival for children with cancer by identifying for clinical testing the most effective agents from among the universe of oncologic agents potentially available for evaluation in children with cancer. The detailed Solicitation (RFP: N01-CM-37027-23) will be available on or about August 20, 2003 on the Research Contracts Branch, NCI website, with a due date for receipt of proposals of October 6, 2003. The web site of the Research Contracts Branch, NCI is: http://rcb.cancer.gov/rcb-internet/ and click Current Request for Proposals. The RFP will include instructions for submission of proposals and evaluation criteria. INQUIRIES For further information, contact: Doris Rosenblatt Contracting Officer Treatment, Biology, and Sciences Section, RCB Executive Plaza South 6120 Executive Blvd. Rockville, MD 20892-7193 E-mail: dr220a@nih.gov Telephone: 301-496-8620 Fax: 301-402-6699
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