DEVELOPMENTAL CENTERS FOR RESEARCH ON COMPLEMENTARY AND ALTERNATIVE MEDICINE (DCRC) RELEASE DATE: October 20, 2003 NOTICE: NOT-AT-04-003 National Center for Complementary and Alternative Medicine (NCCAM) (http://www.nccam.nih.gov/) LETTER OF INTENT RECEIPT DATES: January 17, 2004; January 15, 2005 APPLICATION RECEIPT DATES: February 17, 2004; February 15, 2005 This Notice is to clarify the requirements of Program Announcement PAR-03-046 (http://grants.nih.gov/grants/guide/pa-files/PAR-03-046.html ), and remind applicants that preference may be given to applications proposing research on one of NCCAM’s FY 2004 research priority areas, listed at http://www.nccam.nih.gov/research/priorities/index.htm. Applications substantially similar to those DCRC already funded (listed at http://nccam.nih.gov/training/centers/index.htm) may be given lower program priority. FUNDS AVAILABLE Applications exceeding $600,000 in direct costs in any year will be considered unresponsive and returned without further consideration. Applicants requesting $500,000 or more in direct costs are not required to obtain IC agreement to accept the application. ELIGIBLE INSTITUTIONS AND LEADERSHIP OF DEVELOPMENTAL CENTERS Developmental Centers for Research on Complementary and Alternative Medicine may be directed by a Principal Investigator (P.I.) from an institution devoted to complementary and alternative medicine (CAM; as defined in PAR-03-046) or conventional medicine. An important objective of this program is to facilitate development of the capacity of CAM investigators and CAM institutions to participate in the CAM research enterprise. Therefore applications in which a CAM institution is the applicant organization are especially encouraged. Applications in which the applicant is not a CAM institution will also be considered responsive but should outline thoroughly the strategy for promoting the development of the participating CAM organization(s). STRUCTURAL REQUIREMENTS FOR DEVELOPMENTAL CENTERS NCCAM does not encourage applications for Centers focused on a particular population group unless there is a strong scientific rationale for such a focus. REVIEW CRITERIA FOR INDIVIDUAL RESEARCH PROJECTS In addition to the review criteria enumerated in PAR-03-046, criteria for evaluation of clinical research approaches will include the following: Does the clinical protocol include clear objectives and a trial design and sample size that adequately address those objectives? Does it contain a clear description of interventions, of efficacy and safety parameters and endpoints, and of ethical considerations including monitoring? LETTER OF INTENT Applicants are strongly encouraged to submit a letter of intent, as described in PAR-03-046. The letter of intent should be sent to: Barbara Sorkin, Ph.D. Program Officer Division of Extramural Research and Training National Center for Complementary and Alternative Medicine 6707 Democracy Boulevard, Suite 401 Bethesda, MD 20892-5475 Phone: 301-496-8004 E-mail: sorkinb@mail.nih.gov INQUIRIES Further information about this program is available on the NCCAM website, http://nccam.nci.nih.gov/training/centers/index.htm#4. If you have additional questions regarding the DCRC initiative, please contact: Barbara Sorkin, Ph.D. Program Officer Division of Extramural Research and Training National Center for Complementary and Alternative Medicine 6707 Democracy Boulevard, Suite 401 Bethesda, MD 20892-5475 Phone: 301-496-8004 E-mail: sorkinb@mail.nih.gov For scientific/programmatic questions regarding the responsiveness of your proposal to the DCRC initiative, please contact the appropriate NCCAM Program Officer, listed at http://nccam.nih.gov/research/contact/index.htm. SUPPLEMENTARY INSTRUCTIONS Appendix: the appendix (one for the entire application) may include up to five publications per project and core proposed in the application, consistent with the PHS 398 instructions. The order of materials in the appendix should follow that of the application, i.e., starting with materials relevant to the overall Program, continuing with materials relevant to the individual projects, and concluding with any materials relevant to the core(s). Every appendix item pertaining to a specific project or core must be clearly labeled as such. Please do not staple the appendix. Sections may be separated, for example, by interpolating sheets of colored paper.


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