AMENDMENT #1 TO ASSESSING SAFETY OF CELL SUBSTRATES AND VACCINE COMPONENTS - NIH-NIAID- DAIT-04-22 RELEASE DATE: February 20, 2004 NOTICE: NOT-AI-04-017 National Institute of Allergy and Infectious Diseases (NIAID) (http://www.niaid.nih.gov) RECEIPT DATE: March 1, 2004 DESCRIPTION This amendment provides answers to questions submitted by potential offerors and the responses provided by NIAID. The responses are offered for information only and do not modify or become part of the solicitation. Question 1: In the Statement of Work Part E, on page 13 of 59, does the proposal have to address both E.I.1 (occult adventitious agents) and E.I.2 (TSE) Answer: Offerors may submit a proposal that addresses E.I.1 and/or E.1.2. Question 2: In the Statement of Work Part E, on page 13 of 59, does the proposal have to address multiple assays e.g. 1a 12d and 2a 2b? Answer: As stated in Part E of the Statement of Work (SOW), the multiple assays listed under Part E.I.1 and Part E.I.2 are only examples of potential assays. Offerors may propose none, some, or all of the assays, that are listed as potential examples. Alternatively, offerors may propose other assays, that they believe, meet the criteria outlined in Part E of the SOW. CONTRACTING OFFICE ADDRESS Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases Division of Extramural Activities Contract Management Program 6700-B Rockledge Drive Room 2230, MSC 7612 Bethesda, MD 20892-7605 POINT OF CONTACT Robert Singman, Contract Specialist, Phone 301-451-2607, Fax 301-402-0972, Email rs485j@nih.gov Paul McFarlane, Contracting Officer, Phone 301-496-0349, Fax 301-480-5253, Email pm24@nih.gov

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