RFP ANNOUNCEMENT: HIV VACCINE DESIGN AND DEVELOPMENT TEAMS NIH-NIAID-DAIDS-02-06 Release Date: March 5, 2001 NOTICE: NOT-AI-01-019 National Institute of Allergy and Infectious Diseases Receipt Date: July 9, 2001 The Division of Acquired Immune Deficiency Syndrome (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has a requirement for the development of an efficacious vaccine against HIV for worldwide use in stemming the AIDS epidemic. To augment the vaccine product pipeline, we are seeking opportunities to advance vaccine concepts toward the product stage via a focused, development-based approach. Specifically, the long-range goal of this solicitation is the development of new safe and immunogenic vaccine candidates that merit further evaluation in larger human trials. The HIV Vaccine Design and Development Teams (HVDDT) solicitation seeks to fund consortia of scientists with development experience from industry and/or academia that have 1) identified a promising vaccine concept, and 2) envisioned its targeted development into a vaccine product. A vaccine product is defined here to be a material and its manner of administration that could reasonably provide protection against AIDS. Offerors are encouraged, but not required to conduct phase I/II trials in collaboration with NIAID/DAIDS-supported HIV/AIDS vaccine trials networks. Support for phase III studies will not be funded under this solicitation. It is anticipated that up to six (6) cost reimbursement, completion type contracts will be awarded for a period of five (5) years, beginning approximately February 15, 2002. RFP-NIH-NIAID-DAIDS-02-06 will be available electronically on or about March 12, 2001, and may be accessed through the NIAID Contract Management Branch (CMB) Home Page using the following address http://www.niaid.nih.gov/contract/. Select the link RFPs and then select RFP-NIH-NIAID-DAIDS-02-06. Please note that the RFP for this acquisition has been revised to include only the Work Statement, deliverable and reporting requirements, special requirements and mandatory qualification, if any, the Technical Evaluation Criteria, and the proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on July 9, 2001. Any responsible Offeror may submit a proposal that will be considered by the Government. This advertisement does not commit the Government to award a contract. Point of Contact: Joshua LaVine, Contract Specialist Email: Jl276z@nih.gov Tel: 301-496-2509 (via tty 1-800-735-2258) FAX: 301-402-0972 No collect calls will be accepted.

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