Notice Number: NOT-AG-14-019
Key Dates
Release Date:
July 2, 2014
Estimated Publication Date of Announcement: July 2014
First Estimated Application Due Date: November 2014
Earliest Estimated Award Date: June 2015
Earliest Estimated Start Date: July 2015
Related Announcements
None
Issued by
National Institute on Aging (NIA)
Purpose
The National Institute on Aging (NIA) intends to promote a new initiative by publishing a Funding Opportunity Announcement (FOA) to solicit applications for support of analyses of existing data (or data whose collection will be completed within one year of the FOA publication date) from older populations with high prevalence of mobility disability, low muscle mass and low muscle strength. The purpose is to develop and evaluate cut-points based on analyses of relations of mobility disability to muscle mass and strength. These analyses should extend and expand upon cut-points for low muscle mass and low muscle strength and related analyses published to date.
This Notice is being provided to allow potential applicants sufficient time to plan and coordinate research collaborations and resources.
The FOA is expected to be published in Summer 2014 with an expected application due date in Fall 2014.
This FOA will utilize the U01 activity code.
Research Initiative Details
This Notice targets investigators with experience and expertise in the following areas: studies of the relations between low muscle mass, low muscle strength, and function in older adults; studies of the relations between low muscle mass, weakness, and other aging-related skeletal muscle dysfunctions to mobility disability; geriatrics and clinical-gerontology (scientists and practitioners); bone and mineral research; biostatistics of complex data or of older adults' population with chronic conditions/multimorbidity.
Studies under this FOA should clarify relations between muscle mass and strength, impaired physical function, and mobility disability, and their implications for setting diagnostic cut-points, through analyses of data from populations with substantially more individuals with mobility disability than have been included in previous analyses.
Datasets from multiple populations must contain information on all of the following: at least one objective measure of muscle mass at the same anatomic site(s) common to all included studies; at least one direct measure of muscle strength common to included data sets; gait speed; and self-reported mobility status in populations of older adults. Analyses of relations to other measures of strength, muscle power, and physical performance (e.g., Short Physical Performance Battery), and mobility disability are encouraged. Consortia or partnerships with foreign investigators/organizations will be allowed.
APPLICATIONS ARE NOT BEING SOLICITED AT THIS TIME.
Inquiries
Please direct all inquiries to:
Rosaly Correa-de-Araujo, M.D., M.Sc., Ph.D,
National Institute on Aging (NIA)
Telephone: 301-496-6762
Email: rosaly.correa-de-araujo@nih.gov
and Human Services (HHS)
