SBIR and STTR Success Story for
MIDI, Inc.

(Information Posted/Updated on 08/15/2007)

MIDI, Inc.
125 Sandy Dr.
Newark, DE  19711

Contact:    Myron Sasser
Phone:      302-737-4297
Fax:          302-737-7781
Web Site:

Project Title:  Identification of bacteria direct from blood culture
Related Award(s):  5R44AI046038-03
Technology Developed:
Increased speed of identification of bacteria by 3x and sensitivity by 2.5x. Marketed successfully for two years. Subsequent modification increases speed of sample preparation by 20x and sensitivity by 10x.

Key Words:  Fatty acid analysis, Bacterial identification, Gas chromatography, Sample preparation, Sensitivity, Speed of identification.
Uses of Technology/Products/Service:
Identification of bacteria by gas chromatographic analysis of fatty acid profiles has been improved in terms of sensitivity (20x) in speed of analysis by 3x. Sample preparation time has been reduced from 60 minutes to about 2 minutes. Time for bacterial identification from plate culture is now less than 15 minutes. The next step of the process is to separate the bacteria from the blood in the culture bottle, enabling identification direct-from-blood-culture in less than 30 minutes vs. the normal time of ca. 48 hours.

Benefit to Company:
MIDI was not able to complete all aspects of the research necessary to create the final product during the SBIR Phase II research period. However, marketing of two intermediate products has provided income to help complete the final product development, FDA clearance and marketing. The time frame and expense for such products would not have been feasible without SBIR funding from the National Institute for Allergy and Infectious Diseases.

How Product Was Commercialized:
MIDI commercialized the products through advertising in trade journals and presence at trade shows such as the annual meeting of the American Society for Microbiology.

Past R&D and/or Sales from this Project:   $0.8M
Estimated Future Annual R&D and/or Sales from this Project:   $1.2M